Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry.

Nat Methods
Authors
Keywords
Abstract

Targeted mass spectrometry (MS) is becoming widely used in academia and in pharmaceutical and biotechnology industries for sensitive and quantitative detection of proteins, peptides and post-translational modifications. Here we describe the increasing importance of targeted MS technologies in clinical proteomics and the potential key roles these techniques will have in bridging biomedical discovery and clinical implementation.

Year of Publication
2013
Journal
Nat Methods
Volume
10
Issue
1
Pages
28-34
Date Published
2013 Jan
ISSN
1548-7105
URL
DOI
10.1038/nmeth.2309
PubMed ID
23269374
PubMed Central ID
PMC3943160
Links
Grant list
U24 CA160034 / CA / NCI NIH HHS / United States
R01HL096738 / HL / NHLBI NIH HHS / United States
R01 HL096738 / HL / NHLBI NIH HHS / United States
HHSN268201000033C / PHS HHS / United States
HHSN268201000033C / HL / NHLBI NIH HHS / United States
U24CA160034 / CA / NCI NIH HHS / United States