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Scientific Publications
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GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.
| Publication Type | Journal Article |
| Authors | Fomina-Yadlin, D., Kubicek S., Vetere A., He KH, Schreiber SL, and Wagner BK |
| Abstract | Expression of insulin in terminally differentiated non-beta cell types in the pancreas could be important to treating type-1 diabetes. Previous findings led us to hypothesize involvement of kinase inhibition in induction of insulin expression in pancreatic alpha cells. |
| Year of Publication | 2012 |
| Journal | PloS one |
| Volume | 7 |
| Issue | 1 |
| Pages | e28808 |
| Date Published (YYYY/MM/DD) | 2012/01/01 |
| DOI | 10.1371/journal.pone.0028808 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/22242153?dopt=Abstract |
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