Scientific Publications

Experimental and analytical tools for studying the human microbiome.

Publication TypeJournal Article
AuthorsKuczynski, J., Lauber CL, Walters WA, Parfrey LW, Clemente JC, Gevers D., and Knight R.
AbstractThe human microbiome substantially affects many aspects of human physiology, including metabolism, drug interactions and numerous diseases. This realization, coupled with ever-improving nucleotide sequencing technology, has precipitated the collection of diverse data sets that profile the microbiome. In the past 2 years, studies have begun to include sufficient numbers of subjects to provide the power to associate these microbiome features with clinical states using advanced algorithms, increasing the use of microbiome studies both individually and collectively. Here we discuss tools and strategies for microbiome studies, from primer selection to bioinformatics analysis.
Year of Publication2011
JournalNature reviews. Genetics
Volume13
Issue1
Pages47-58
Date Published (YYYY/MM/DD)2011/12/16
ISSN Number1471-0056
DOI10.1038/nrg3129
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/22179717?dopt=Abstract