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Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
| Publication Type | Journal Article |
| Authors | Cho, YJ, Tsherniak A., Tamayo P., Santagata S., Ligon A., Greulich H., Berhoukim R., Amani V., Goumnerova L., Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A., Delattre O., Kool M., Ligon K., Meyerson M., Mesirov J. P., and Pomeroy SL |
| Abstract | Medulloblastomas are heterogeneous tumors that collectively represent the most common malignant brain tumor in children. To understand the molecular characteristics underlying their heterogeneity and to identify whether such characteristics represent risk factors for patients with this disease, we performed an integrated genomic analysis of a large series of primary tumors. |
| Year of Publication | 2011 |
| Journal | Journal of clinical oncology : official journal of the American Society of Clinical Oncology |
| Volume | 29 |
| Issue | 11 |
| Pages | 1424-30 |
| Date Published (YYYY/MM/DD) | 2011/04/10 |
| ISSN Number | 0732-183X |
| DOI | 10.1200/JCO.2010.28.5148 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/21098324?dopt=Abstract |
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