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| Publication Type | Journal Article |
| Authors | Gillette, MA, Mani D. R., and Carr SA |
| Abstract | The role of pattern in biomarker discovery and clinical diagnosis is examined in its historical context. The use of MS-derived pattern is treated as a logical extension of prior applications of non-MS-derived pattern. Criticisms pertaining to specific technology platforms and analytic methodologies are considered separately from the larger issues of pattern utility and deployment in biomarker discovery. We present a hybrid strategy that marries the desirable attributes of high-information content MS pattern with the capability to obtain identity, and explore the key steps in establishing a data analysis pipeline for pattern-based biomarker discovery. |
| Year of Publication | 1969 |
| Journal | Journal of proteome research |
| Volume | 4 |
| Issue | 4 |
| Pages | 1143-54 |
| Date Published (YYYY/MM/DD) | 2005/1/1 |
| ISSN Number | 1535-3893 |
| DOI | 10.1021/pr0500962 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/16083265?dopt=Abstract |
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