Synthesis of kaempferitrin.

J Org Chem
Authors
Keywords
Abstract

A short synthesis of Kaempferitrin (1), a 3,7-diglycosylflavone, is reported. Key features include the synthesis of a protected form of kaempferol in which all four hydroxy groups are differentiated and the first bis-glycosylation of a dihydroxyflavone. This synthesis will allow the preparation of derivatives for further explorations into the origins of this compound's biological activity.

Year of Publication
2007
Journal
J Org Chem
Volume
72
Issue
12
Pages
4582-5
Date Published
2007 Jun 08
ISSN
0022-3263
URL
DOI
10.1021/jo070502w
PubMed ID
17497804
Links
Grant list
P50 GM069721 / GM / NIGMS NIH HHS / United States
R03 AI062905-01 / AI / NIAID NIH HHS / United States