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Cross-kingdom patterns of alternative splicing and splice recognition.
| Publication Type | Journal Article |
| Authors | McGuire, AM, Pearson MD, Neafsey DE, and Galagan JE |
| Abstract | Variations in transcript splicing can reveal how eukaryotes recognize intronic splice sites. Retained introns (RIs) commonly appear when the intron definition (ID) mechanism of splice site recognition inconsistently identifies intron-exon boundaries, and cassette exons (CEs) are often caused by variable recognition of splice junctions by the exon definition (ED) mechanism. We have performed a comprehensive survey of alternative splicing across 42 eukaryotes to gain insight into how spliceosomal introns are recognized. |
| Year of Publication | 2012 |
| Journal | Genome biology |
| Volume | 9 |
| Issue | 3 |
| Pages | R50 |
| Date Published (YYYY/MM/DD) | 2012/01/05 |
| ISSN Number | 1465-6906 |
| DOI | 10.1186/gb-2008-9-3-r50 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/18321378?dopt=Abstract |
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