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Cross-kingdom patterns of alternative splicing and splice recognition.
|Publication Type||Journal Article|
|Authors||McGuire, AM, Pearson MD, Neafsey DE, and Galagan JE|
|Abstract||Variations in transcript splicing can reveal how eukaryotes recognize intronic splice sites. Retained introns (RIs) commonly appear when the intron definition (ID) mechanism of splice site recognition inconsistently identifies intron-exon boundaries, and cassette exons (CEs) are often caused by variable recognition of splice junctions by the exon definition (ED) mechanism. We have performed a comprehensive survey of alternative splicing across 42 eukaryotes to gain insight into how spliceosomal introns are recognized.|
|Year of Publication||2012|
|Date Published (YYYY/MM/DD)||2012/01/05|