Scientific Publications

Zinc-catalyzed silylation of terminal alkynes.

Publication TypeJournal Article
AuthorsRahaim RJ, Jr, and Shaw JT
AbstractA rapid and high-yielding silylation of terminal alkynes employing TMSOTf and catalytic quantities of Zn(OTf)2 has been developed. The reaction works well for a variety of substrates including reactive esters. Fifteen examples with yields of >90% are reported.
Year of Publication2008
JournalThe Journal of organic chemistry
Volume73
Issue7
Pages2912-5
Date Published (YYYY/MM/DD)2008/04/04
ISSN Number0022-3263
DOI10.1021/jo702557d
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/18331056?dopt=Abstract