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A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking.
| Publication Type | Journal Article |
| Authors | Daniels, R., Volkman SK, Milner DA, Mahesh N., Neafsey DE, Park DJ, Rosen D., Angelino E., Sabeti PC, Wirth DF, and Wiegand RC |
| Abstract | Single nucleotide polymorphism (SNP) genotyping provides the means to develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium falciparum parasite using a small amount of DNA. Such an assay could be used to distinguish recrudescence from re-infection in drug trials, to monitor the frequency and distribution of specific parasites in a patient population undergoing drug treatment or vaccine challenge, or for tracking samples and determining purity of isolates in the laboratory during culture adaptation and sub-cloning, as well as routine passage. |
| Year of Publication | 2008 |
| Journal | Malaria journal |
| Volume | 7 |
| Pages | 223 |
| Date Published (YYYY/MM/DD) | 2008/10/29 |
| DOI | 10.1186/1475-2875-7-223 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/18959790?dopt=Abstract |
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