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microRNA expression during trophectoderm specification.
|Publication Type||Journal Article|
|Authors||Viswanathan, SR, Mermel CH, Lu J., Lu CW, Golub T. R., and Daley GQ|
|Abstract||Segregation of the trophectoderm from the inner cell mass of the embryo represents the first cell-fate decision of mammalian development. Transcription factors essential for specifying trophectoderm have been identified, but the role of microRNAs (miRNAs) in modulating this fate-choice has been largely unexplored. We have compared miRNA expression in embryonic stem cell (ESC)-derived trophectoderm and in staged murine embryos to identify a set of candidate miRNAs likely to be involved in trophectoderm specification.|
|Year of Publication||2009|
|Date Published (YYYY/MM/DD)||2009/07/03|