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microRNA expression during trophectoderm specification.
| Publication Type | Journal Article |
| Authors | Viswanathan, SR, Mermel CH, Lu J., Lu CW, Golub T. R., and Daley GQ |
| Abstract | Segregation of the trophectoderm from the inner cell mass of the embryo represents the first cell-fate decision of mammalian development. Transcription factors essential for specifying trophectoderm have been identified, but the role of microRNAs (miRNAs) in modulating this fate-choice has been largely unexplored. We have compared miRNA expression in embryonic stem cell (ESC)-derived trophectoderm and in staged murine embryos to identify a set of candidate miRNAs likely to be involved in trophectoderm specification. |
| Year of Publication | 2009 |
| Journal | PloS one |
| Volume | 4 |
| Issue | 7 |
| Pages | e6143 |
| Date Published (YYYY/MM/DD) | 2009/07/03 |
| DOI | 10.1371/journal.pone.0006143 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/19582159?dopt=Abstract |




