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Scientific Publications
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Copper-mediated amidation of heterocyclic and aromatic C-H bonds.
| Publication Type | Journal Article |
| Authors | Wang, Q., and Schreiber SL |
| Abstract | A copper-mediated aerobic coupling reaction enables direct amidation of heterocycles or aromatics having weakly acidic C-H bonds with a variety of nitrogen nucleophiles. These reactions provide efficient access to many biologically important skeletons, including ones with the potential to serve as inhibitors of HMTs. |
| Year of Publication | 2009 |
| Journal | Organic letters |
| Volume | 11 |
| Issue | 22 |
| Pages | 5178-80 |
| Date Published (YYYY/MM/DD) | 2009/11/19 |
| ISSN Number | 1523-7060 |
| DOI | 10.1021/ol902079g |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/19860425?dopt=Abstract |
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