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Aziridines as intermediates in diversity-oriented syntheses of alkaloids.
| Publication Type | Journal Article |
| Authors | Taylor, AM, and Schreiber SL |
| Abstract | The efficient synthesis of small molecules that collectively comprise optimal small-molecule screening collections is an important goal. With this in mind, we have used N-alkyl aziridines in a regio- and stereochemically controlled synthesis of polycyclic heterocycles based on nucleophilic ring opening and subsequent intramolecular cyclization. |
| Year of Publication | 2009 |
| Journal | Tetrahedron letters |
| Volume | 50 |
| Issue | 26 |
| Pages | 3230-3233 |
| Date Published (YYYY/MM/DD) | 2009/07/02 |
| ISSN Number | 0040-4039 |
| DOI | 10.1016/j.tetlet.2009.02.034 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/20046991?dopt=Abstract |
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