Scientific Publications

CK1epsilon is required for breast cancers dependent on beta-catenin activity.

Publication TypeJournal Article
AuthorsKim, SY, Dunn IF, Firestein R., Gupta P., Wardwell L., Repich K., Schinzel AC, Wittner B., Silver SJ, Root DE, Boehm JS, Ramaswamy S., Lander E. S., and Hahn WC
AbstractAberrant beta-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate beta-catenin activity for therapeutic purposes have proven elusive to date.
Year of Publication2010
JournalPloS one
Volume5
Issue2
Pagese8979
Date Published (YYYY/MM/DD)2010/02/01
DOI10.1371/journal.pone.0008979
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/20126544?dopt=Abstract