Scientific Publications

Genome-wide synteny through highly sensitive sequence alignment: Satsuma.

Publication TypeJournal Article
AuthorsGrabherr, MG, Russell P., Meyer M., Mauceli E., Alföldi J., Di Palma F., and Lindblad-Toh K.
AbstractComparative genomics heavily relies on alignments of large and often complex DNA sequences. From an engineering perspective, the problem here is to provide maximum sensitivity (to find all there is to find), specificity (to only find real homology) and speed (to accommodate the billions of base pairs of vertebrate genomes).
Year of Publication2010
JournalBioinformatics (Oxford, England)
Volume26
Issue9
Pages1145-51
Date Published (YYYY/MM/DD)2010/05/01
ISSN Number1367-4803
DOI10.1093/bioinformatics/btq102
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/20208069?dopt=Abstract