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Stereochemical and skeletal diversity arising from amino propargylic alcohols.
| Publication Type | Journal Article |
| Authors | Pizzirani, D., Kaya T., Clemons PA, and Schreiber SL |
| Abstract | An efficient synthetic pathway to the possible stereoisomers of skeletally diverse heterocyclic small molecules is presented. The change in shape brought about by different intramolecular cyclizations of diastereoisomeric amino propargylic alcohols is quantified using principal moment-of-inertia (PMI) shape analysis. |
| Year of Publication | 2010 |
| Journal | Organic letters |
| Volume | 12 |
| Issue | 12 |
| Pages | 2822-5 |
| Date Published (YYYY/MM/DD) | 2010/06/18 |
| ISSN Number | 1523-7060 |
| DOI | 10.1021/ol100914b |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/20481457?dopt=Abstract |
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