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Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions.
| Publication Type | Journal Article |
| Authors | Muncipinto, G., Kaya T., Wilson JA, Kumagai N., Clemons PA, and Schreiber SL |
| Abstract | A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis. |
| Year of Publication | 2010 |
| Journal | Organic letters |
| Volume | 12 |
| Issue | 22 |
| Pages | 5230-3 |
| Date Published (YYYY/MM/DD) | 2010/11/19 |
| ISSN Number | 1523-7060 |
| DOI | 10.1021/ol102266j |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/20977261?dopt=Abstract |
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