Scientific Publications

Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions.

Publication TypeJournal Article
AuthorsMuncipinto, G., Kaya T., Wilson JA, Kumagai N., Clemons PA, and Schreiber SL
AbstractA short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.
Year of Publication2010
JournalOrganic letters
Volume12
Issue22
Pages5230-3
Date Published (YYYY/MM/DD)2010/11/19
ISSN Number1523-7060
DOI10.1021/ol102266j
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/20977261?dopt=Abstract