Scientific Publications

Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.

Publication TypeJournal Article
AuthorsGomez, JE, Clatworthy A., and Hung DT
AbstractClassical genetic approaches for studying bacterial pathogenesis have provided a solid foundation for our current understanding of microbial physiology and the interactions between pathogen and host. During the past decade however, advances in several arenas have expanded the ways in which the biology of pathogens can be studied. This review discussed the impact of these advances on bacterial genetics, including the application of genomics and chemical biology to the study of pathogenesis.
Year of Publication2011
JournalCritical reviews in biochemistry and molecular biology
Volume46
Issue1
Pages41-66
Date Published (YYYY/MM/DD)2011/02/01
ISSN Number1040-9238
DOI10.3109/10409238.2010.538663
PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/21250782?dopt=Abstract