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Read More / View Supplemental Materials - Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
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| Publication Type | Journal Article |
| Authors | Meissner, A. |
| Abstract | How DNA methyltransferases, with their limited target specificity, establish cell-type-specific epigenetic patterns is poorly understood. Schübeler and colleagues (Lienert et al., 2011) now show that methylation-determining regions (MDRs) within promoter regions are sufficient to recapitulate endogenous patterns and dynamics of DNA methylation. |
| Year of Publication | 2011 |
| Journal | Cell stem cell |
| Volume | 9 |
| Issue | 5 |
| Pages | 388-90 |
| Date Published (YYYY/MM/DD) | 2011/11/04 |
| ISSN Number | 1934-5909 |
| DOI | 10.1016/j.stem.2011.10.014 |
| PubMed | http://www.ncbi.nlm.nih.gov/pubmed/22056134?dopt=Abstract |
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