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  • Showing 1-30 of 30 Results
2011
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.Urgaonkar, S., Cortese JF, Patel V., Ross L., Clish CB, Serrano AE, Cromwell M., Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials
Abstract
A method for high-throughput gene expression signature analysis.Peck, D., Crawford ED, Ross KN, Stegmaier K., Golub T. R., and Lamb J. Genome biology, 2011/12/08, Volume 7, Issue 7, p.R61, (2011) Read More / View Supplemental Materials
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2010
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Marcaurelle, LA, Comer E., Dandapani S., Duvall JR, Gerard B., Kesavan S., Lee MD 4th, Liu H., Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A., Ryba TD, Suh BC, Wei J., Young DW, Akella LB, Ross NT, Zhang YL, et al. Journal of the American Chemical Society, 2010/12/01, Volume 132, Issue 47, p.16962-76, (2010) Read More / View Supplemental Materials
Abstract
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.Bradner, JE, Mak R., Tanguturi SK, Mazitschek R., Haggarty SJ, Ross K., Chang CY, Bosco J., West N., Morse E., Lin K., Shen JP, Kwiatkowski NP, Gheldof N., Dekker J., DeAngelo DJ, Carr SA, Schreiber SL, Golub T. R., and Ebert BL Proceedings of the National Academy of Sciences of the United States of America, 2010/07/13, Volume 107, Issue 28, p.12617-22, (2010) Read More / View Supplemental Materials
Abstract
Genetic structure of a unique admixed population: implications for medical research.Patterson, N., Petersen DC, van der Ross RE, Sudoyo H., Glashoff RH, Marzuki S., Reich D., and Hayes VM Human molecular genetics, 2010/02/01, Volume 19, Issue 3, p.411-9, (2010) Read More / View Supplemental Materials
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2009
Proteomic and genetic approaches identify Syk as an AML target.Hahn, CK, Berchuck JE, Ross KN, Kakoza RM, Clauser K., Schinzel AC, Ross L., Galinsky I., Davis TN, Silver SJ, Root DE, Stone RM, DeAngelo DJ, Carroll M., Hahn WC, Carr SA, Golub T. R., Kung AL, and Stegmaier K. Cancer cell, 2009/10/06, Volume 16, Issue 4, p.281-94, (2009) Read More / View Supplemental Materials
Abstract
Identification of AML1-ETO modulators by chemical genomics.Corsello, SM, Roti G., Ross KN, Chow KT, Galinsky I., DeAngelo DJ, Stone RM, Kung AL, Golub T. R., and Stegmaier K. Blood, 2009/06/11, Volume 113, Issue 24, p.6193-205, (2009) Read More / View Supplemental Materials
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2008
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiationHahn, Cynthia K., Ross Kenneth N., Warrington Ian M., Mazitschek Ralph, Kanegai Cindy M., Wright Renee D., Kung Andrew L., Golub Todd R., and Stegmaier Kimberly Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15/, Volume 105, Issue 28, p.9751 - 6, (2008) Read More / View Supplemental Materials
Abstract
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.Hahn, CK, Ross KN, Warrington IM, Mazitschek R., Kanegai CM, Wright RD, Kung AL, Golub T. R., and Stegmaier K. Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15, Volume 105, Issue 28, p.9751-6, (2008) Read More / View Supplemental Materials
Abstract
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastasesXu, Lei, Shen Steven S., Hoshida Yujin, Subramanian Aravind, Ross Ken, Brunet Jean-Philippe, Wagner Stephan N., Ramaswamy Sridhar, Mesirov Jill P., and Hynes Richard O. Molecular Cancer Research: MCR, 2008/05//, Volume 6, Issue 5, p.760 - 9, (2008) Read More / View Supplemental Materials
Abstract
Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma MetastasesLei Xu, Steven S. Shen, Yujin Hoshida Aravind Subramanian Ken Ross Jean-Philippe Brunet Stephan Wagner Sridhar Ramaswamy N., and Hynes Richard O., Volume 6, Issue May 1, p.760-769, (2008) Read More / View Supplemental Materials
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2007
Evolution of genes and genomes on the Drosophila phylogeny.Drosophila 12 Genomes, Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B., Markow TA, Kaufman TC, Kellis M., Gelbart W., Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B., Aguade M., Akashi H., et al. Nature, 2007/11/08, Volume 450, Issue 7167, p.203-18, (2007) Read More / View Supplemental Materials
Abstract
Identification of prostate cancer modifier pathways using parental strain expression mapping.Xu, Q., Majumder PK, Ross K., Shim Y., Golub T. R., Loda M., and Sellers WR Proceedings of the National Academy of Sciences of the United States of America, 2007/11/06, Volume 104, Issue 45, p.17771-6, (2007) Read More / View Supplemental Materials
Abstract
Genome-wide detection and characterization of positive selection in human populations.Sabeti, PC, Varilly P., Fry B., Lohmueller J., Hostetter E., Cotsapas C., Xie X., Byrne EH, McCarroll SA, Gaudet R., Schaffner SF, Lander E. S., International HapMap Consortium, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, et al. Nature, 2007/10/18, Volume 449, Issue 7164, p.913-8, (2007) Read More / View Supplemental Materials
Abstract
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.Stegmaier, K., Wong JS, Ross KN, Chow KT, Peck D., Wright RD, Lessnick SL, Kung AL, and Golub T. R. PLoS medicine, 2007/04/01, Volume 4, Issue 4, p.e122, (2007) Read More / View Supplemental Materials
Abstract
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaStegmaier, Kimberly, Wong Jenny S., Ross Kenneth N., Chow Kwan T., Peck David, Wright Renee D., Lessnick Stephen L., Kung Andrew L., and Golub Todd R. PLoS Medicine, 2007/04//, Volume 4, Issue 4, p.e122 - e122, (2007) Read More / View Supplemental Materials
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2006
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.Hieronymus, H., Lamb J., Ross KN, Peng XP, Clement C., Rodina A., Nieto M., Du J., Stegmaier K., Raj SM, Maloney KN, Clardy J., Hahn WC, Chiosis G., and Golub T. R. Cancer cell, 2006/10/01, Volume 10, Issue 4, p.321-30, (2006) Read More / View Supplemental Materials
Abstract
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsHieronymus, Haley, Lamb Justin, Ross Kenneth N., Peng Xiao P., Clement Cristina, Rodina Anna, Nieto Maria, Du Jinyan, Stegmaier Kimberly, Raj Srilakshmi M., Maloney Katherine N., Clardy Jon, Hahn William C., Chiosis Gabriela, and Golub Todd R. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.321 - 30, (2006) Read More / View Supplemental Materials
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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and diseaseLamb, Justin, Crawford Emily D., Peck David, Modell Joshua W., Blat Irene C., Wrobel Matthew J., Lerner Jim, Brunet Jean-Philippe, Subramanian Aravind, Ross Kenneth N., Reich Michael, Hieronymus Haley, Wei Guo, Armstrong Scott A., Haggarty Stephen J., and Clemons Pau Science (New York, N.Y.), 2006/09/29/, Volume 313, Issue 5795, p.1929 - 35, (2006) Read More / View Supplemental Materials
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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.Lamb, J., Crawford ED, Peck D., Modell JW, Blat IC, Wrobel MJ, Lerner J., Brunet JP, Subramanian A., Ross KN, Reich M., Hieronymus H., Wei G., Armstrong SA, Haggarty SJ, Clemons PA, Wei R., Carr SA, Lander E. S., and Golub T. R. Science (New York, N.Y.), 2006/09/29, Volume 313, Issue 5795, p.1929-35, (2006) Read More / View Supplemental Materials
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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer.Stanbrough, M., Bubley GJ, Ross K., Golub T. R., Rubin MA, Penning TM, Febbo PG, and Balk SP Cancer research, 2006/03/01, Volume 66, Issue 5, p.2815-25, (2006) Read More / View Supplemental Materials
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2005
Gefitinib induces myeloid differentiation of acute myeloid leukemiaStegmaier, Kimberly, Corsello Steven M., Ross Kenneth N., Wong Jenny S., Deangelo Daniel J., and Golub Todd R. Blood, 2005/10/15/, Volume 106, Issue 8, p.2841 - 8, (2005) Read More / View Supplemental Materials
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Gefitinib induces myeloid differentiation of acute myeloid leukemia.Stegmaier, K., Corsello SM, Ross KN, Wong JS, DeAngelo DJ, and Golub T. R. Blood, 2005/10/15, Volume 106, Issue 8, p.2841-8, (2005) Read More / View Supplemental Materials
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2004
Identification of AML1-ETO Modulators with Chemical GenomicsCorsello, Steven M., Roti Giovanni, Ross Kenneth N., Chow Kwan T., Golub Todd R., and Stegmaier Kimberly, unknown, (2004) Read More / View Supplemental Materials
Abstract
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.Du, J., Widlund HR, Horstmann MA, Ramaswamy S., Ross K., Huber WE, Nishimura EK, Golub T. R., and Fisher DE Cancer cell, 2004/12/01, Volume 6, Issue 6, p.565-76, (2004) Read More / View Supplemental Materials
Abstract
Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.Stegmaier, K., Ross KN, Colavito SA, O'Malley S., Stockwell BR, and Golub T. R. Nature genetics, 2004/03/01, Volume 36, Issue 3, p.257-63, (2004) Read More / View Supplemental Materials
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Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiationStegmaier, Kimberly, Ross Kenneth N., Colavito Sierra A., O'Malley Shawn, Stockwell Brent R., and Golub Todd R. Nature Genetics, 2004/03//, Volume 36, Issue 3, p.257 - 63, (2004) Read More / View Supplemental Materials
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2003
A molecular signature of metastasis in primary solid tumorsRamaswamy, Sridhar, Ross Ken N., Lander Eric S., and Golub Todd R. Nature Genetics, 2003/01//, Volume 33, Issue 1, p.49 - 54, (2003) Read More / View Supplemental Materials
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2002
Gene expression correlates of clinical prostate cancer behaviorSingh, Dinesh, Febbo Phillip G., Ross Kenneth, Jackson Donald G., Manola Judith, Ladd Christine, Tamayo Pablo, Renshaw Andrew A., D'Amico Anthony V., Richie Jerome P., Lander Eric S., Loda Massimo, Kantoff Philip W., Golub Todd R., and Sellers William R. Cancer Cell, 2002/03//, Volume 1, Issue 2, p.203 - 9, (2002) Read More / View Supplemental Materials
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Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learningShipp, Margaret A., Ross Ken N., Tamayo Pablo, Weng Andrew P., Kutok Jeffery L., Aguiar Ricardo C. T., Gaasenbeek Michelle, Angelo Michael, Reich Michael, Pinkus Geraldine S., Ray Tane S., Koval Margaret A., Last Kim W., Norton Andrew, Lister Andrew T., and Mesirov Jill Nature Medicine, 2002/01//, Volume 8, Issue 1, p.68 - 74, (2002) Read More / View Supplemental Materials
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  • Showing 1-30 of 30 Results