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  • Showing 1-11 of 11 Results
2011
Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase.Peng, LF, Schaefer EA, Maloof N., Skaff A., Berical A., Belon CA, Heck JA, Lin W., Frick DN, Allen TM, Miziorko HM, Schreiber SL, and Chung RT The Journal of infectious diseases, 2011/08/15, Volume 204, Issue 4, p.609-16, (2011) Read More / View Supplemental Materials
Abstract
2009
Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog.Peng, LF, Stanton BZ, Maloof N., Wang X., and Schreiber SL Bioorganic & medicinal chemistry letters, 2009/11/15, Volume 19, Issue 22, p.6319-25, (2009) Read More / View Supplemental Materials
Abstract
A small molecule that directs differentiation of human ESCs into the pancreatic lineage.Chen, S., Borowiak M., Fox JL, Maehr R., Osafune K., Davidow L., Lam K., Peng LF, Schreiber SL, Rubin LL, and Melton D. Nature chemical biology, 2009/04/01, Volume 5, Issue 4, p.258-65, (2009) Read More / View Supplemental Materials
Abstract
A small molecule that binds Hedgehog and blocks its signaling in human cells.Stanton, BZ, Peng LF, Maloof N., Nakai K., Wang X., Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A., and Schreiber SL Nature chemical biology, 2009/03/01, Volume 5, Issue 3, p.154-6, (2009) Read More / View Supplemental Materials
Abstract
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.Du, J., Bernasconi P., Clauser KR, Mani D. R., Finn SP, Beroukhim R., Burns M., Julian B., Peng XP, Hieronymus H., Maglathlin RL, Lewis TA, Liau LM, Nghiemphu P., Mellinghoff IK, Louis DN, Loda M., Carr SA, Kung AL, and Golub T. R. Nature biotechnology, 2009/01/01, Volume 27, Issue 1, p.77-83, (2009) Read More / View Supplemental Materials
Abstract
2008
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Lu, J., Guo S., Ebert BL, Zhang H., Peng X., Bosco J., Pretz J., Schlanger R., Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, and Golub T. R. Developmental cell, 2008/06/01, Volume 14, Issue 6, p.843-53, (2008) Read More / View Supplemental Materials
Abstract
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitorsLu, Jun, Guo Shangqin, Ebert Benjamin L., Zhang Hao, Peng Xiao, Bosco Jocelyn, Pretz Jennifer, Schlanger Rita, Wang Judy Y., Mak Raymond H., Dombkowski David M., Preffer Frederic I., Scadden David T., and Golub Todd R. Developmental Cell, 2008/06//, Volume 14, Issue 6, p.843 - 53, (2008) Read More / View Supplemental Materials
Abstract
2007
Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen.Peng, LF, Kim SS, Matchacheep S., Lei X., Su S., Lin W., Runguphan W., Choe WH, Sakamoto N., Ikeda M., Kato N., Beeler AB, Porco JA Jr, Schreiber SL, and Chung RT Antimicrobial agents and chemotherapy, 2007/10/01, Volume 51, Issue 10, p.3756-9, (2007) Read More / View Supplemental Materials
Abstract
A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication.Kim, SS, Peng LF, Lin W., Choe WH, Sakamoto N., Kato N., Ikeda M., Schreiber SL, and Chung RT Gastroenterology, 2007/01/01, Volume 132, Issue 1, p.311-20, (2007) Read More / View Supplemental Materials
Abstract
2006
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.Hieronymus, H., Lamb J., Ross KN, Peng XP, Clement C., Rodina A., Nieto M., Du J., Stegmaier K., Raj SM, Maloney KN, Clardy J., Hahn WC, Chiosis G., and Golub T. R. Cancer cell, 2006/10/01, Volume 10, Issue 4, p.321-30, (2006) Read More / View Supplemental Materials
Abstract
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsHieronymus, Haley, Lamb Justin, Ross Kenneth N., Peng Xiao P., Clement Cristina, Rodina Anna, Nieto Maria, Du Jinyan, Stegmaier Kimberly, Raj Srilakshmi M., Maloney Katherine N., Clardy Jon, Hahn William C., Chiosis Gabriela, and Golub Todd R. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.321 - 30, (2006) Read More / View Supplemental Materials
Abstract
  • Showing 1-11 of 11 Results