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  • Showing 1-11 of 11 Results
2011
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.Urgaonkar, S., Cortese JF, Patel V., Ross L., Clish CB, Serrano AE, Cromwell M., Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials
Abstract
2010
A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity.Urgaonkar, S., Cortese JF, Barker RH, Cromwell M., Serrano AE, Wirth DF, Clardy J., and Mazitschek R. Organic letters, 2010/09/17, Volume 12, Issue 18, p.3998-4001, (2010) Read More / View Supplemental Materials
Abstract
Antiplasmodial activity of piperazine sulfonamides.Martyn, DC, Cortese JF, Tyndall E., Dick J., Mazitschek R., Munoz B., and Clardy J. Bioorganic & medicinal chemistry letters, 2010/01/01, Volume 20, Issue 1, p.218-21, (2010) Read More / View Supplemental Materials
Abstract
Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.Martyn, DC, Nijjar A., Celatka CA, Mazitschek R., Cortese JF, Tyndall E., Liu H., Fitzgerald MM, O'Shea TJ, Danthi S., and Clardy J. Bioorganic & medicinal chemistry letters, 2010/01/01, Volume 20, Issue 1, p.228-31, (2010) Read More / View Supplemental Materials
Abstract
2009
Synthesis and in vitro DMPK profiling of a 1,2-dioxolane-based library with activity against Plasmodium falciparum.Martyn, DC, Beletsky G., Cortese JF, Tyndall E., Liu H., Fitzgerald MM, O'Shea TJ, Liang B., and Clardy J. Bioorganic & medicinal chemistry letters, 2009/10/01, Volume 19, Issue 19, p.5657-60, (2009) Read More / View Supplemental Materials
Abstract
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.Patel, V., Mazitschek R., Coleman B., Nguyen C., Urgaonkar S., Cortese J., Barker RH, Greenberg E., Tang W., Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, and Clardy J. Journal of medicinal chemistry, 2009/04/23, Volume 52, Issue 8, p.2185-7, (2009) Read More / View Supplemental Materials
Abstract
2008
Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum.Martyn, DC, Ramirez AP, Beattie MJ, Cortese JF, Patel V., Rush MA, Woerpel KA, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/12/15, Volume 18, Issue 24, p.6521-4, (2008) Read More / View Supplemental Materials
Abstract
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.Mazitschek, R., Patel V., Wirth DF, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/05/01, Volume 18, Issue 9, p.2809-12, (2008) Read More / View Supplemental Materials
Abstract
2007
Detecting binding interactions using microarrays of natural product extracts.Schmitz, K., Haggarty SJ, McPherson OM, Clardy J., and Koehler AN Journal of the American Chemical Society, 2007/09/19, Volume 129, Issue 37, p.11346-7, (2007) Read More / View Supplemental Materials
2006
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.Hieronymus, H., Lamb J., Ross KN, Peng XP, Clement C., Rodina A., Nieto M., Du J., Stegmaier K., Raj SM, Maloney KN, Clardy J., Hahn WC, Chiosis G., and Golub T. R. Cancer cell, 2006/10/01, Volume 10, Issue 4, p.321-30, (2006) Read More / View Supplemental Materials
Abstract
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsHieronymus, Haley, Lamb Justin, Ross Kenneth N., Peng Xiao P., Clement Cristina, Rodina Anna, Nieto Maria, Du Jinyan, Stegmaier Kimberly, Raj Srilakshmi M., Maloney Katherine N., Clardy Jon, Hahn William C., Chiosis Gabriela, and Golub Todd R. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.321 - 30, (2006) Read More / View Supplemental Materials
Abstract
  • Showing 1-11 of 11 Results