New Publications

Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers.
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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
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Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells.
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Absolute quantification of somatic DNA alterations in human cancer.
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RNA-SeQC: RNA-seq metrics for quality control and process optimization.
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Scientific Publications

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2012

RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.Barczak, AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L., Borowsky ML, Onderdonk AB, Stanley SA, Kaur D., Bryant KF, Knipe DM, Sloutsky A., and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2012/04/17, Volume 109, Issue 16, p.6217-22, (2012) Read More / View Supplemental Materials

Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.Grad, YH, Lipsitch M., Feldgarden M., Arachchi HM, Cerqueira GC, FitzGerald M., Godfrey P., Haas BJ, Murphy CI, Russ C., Sykes S., Walker BJ, Wortman JR, Young S., Zeng Q., Abouelleil A., Bochicchio J., Chauvin S., Desmet T., Gujja S., et al. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.3065-70, (2012) Read More / View Supplemental Materials

2011

The two-component sensor kinase KinB acts as a non-canonical switch between acute and chronic infection.Chand, NS, and Hung DT Virulence, 2011/11/01, Volume 2, Issue 6, p.553-8, (2011) Read More / View Supplemental Materials

Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.Gomez, JE, Clatworthy A., and Hung DT Critical reviews in biochemistry and molecular biology, 2011/02/01, Volume 46, Issue 1, p.41-66, (2011) Read More / View Supplemental Materials

2010

The fast track to multidrug resistance.Kaufmann, BB, and Hung DT Molecular cell, 2010/02/12, Volume 37, Issue 3, p.297-8, (2010) Read More / View Supplemental Materials

2009

Toward a systems-level analysis of infection biology: a new method for conducting genetic screens in human cells.Stanley, SA, and Hung DT Science translational medicine, 2009/12/16, Volume 1, Issue 11, p.11ps13, (2009) Read More / View Supplemental Materials

Chemical tools for dissecting bacterial physiology and virulence.Stanley, SA, and Hung DT Biochemistry, 2009/09/22, Volume 48, Issue 37, p.8776-86, (2009) Read More / View Supplemental Materials

Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.Nusbaum, C., Ohsumi TK, Gomez J., Aquadro J., Victor TC, Warren RM, Hung DT, Birren BW, Lander E. S., and Jaffe DB Nature methods, 2009/01/01, Volume 6, Issue 1, p.67-9, (2009) Read More / View Supplemental Materials