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  • Showing 1-18 of 18 Results
2013
From genetics of inflammatory bowel disease towards mechanistic insights.Graham, DB, and Xavier RJ Trends in immunology, 2013/04/29, (2013) Read More / View Supplemental Materials
Abstract
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.Kirby, A., Gnirke A., Jaffe DB, Barešová V., Pochet N., Blumenstiel B., Ye C., Aird D., Stevens C., Robinson JT, Cabili MN, Gat-Viks I., Kelliher E., Daza R., DeFelice M., Hůlková H., Sovová J., Vylet'al P., Antignac C., Guttman M., et al. Nature genetics, 2013/03/01, Volume 45, Issue 3, p.299-303, (2013) Read More / View Supplemental Materials
Abstract
ATG5 regulates plasma cell differentiation.Conway, KL, Kuballa P., Khor B., Zhang M., Shi HN, Virgin HW, and Xavier RJ Autophagy, 2013/01/17, Volume 9, Issue 4, (2013) Read More / View Supplemental Materials
Abstract
2012
The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium.Huett, A., Heath RJ, Begun J., Sassi SO, Baxt LA, Vyas JM, Goldberg MB, and Xavier RJ Cell host & microbe, 2012/12/13, Volume 12, Issue 6, p.778-90, (2012) Read More / View Supplemental Materials
Abstract
Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes.Kleinnijenhuis, J., Quintin J., Preijers F., Joosten LA, Ifrim DC, Saeed S., Jacobs C., van Loenhout J., de Jong D., Stunnenberg HG, Xavier RJ, van der Meer JW, van Crevel R., and Netea MG Proceedings of the National Academy of Sciences of the United States of America, 2012/10/23, Volume 109, Issue 43, p.17537-42, (2012) Read More / View Supplemental Materials
Abstract
p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation.Conway, KL, Goel G., Sokol H., Manocha M., Mizoguchi E., Terhorst C., Bhan AK, Gardet A., and Xavier RJ Journal of immunology (Baltimore, Md. : 1950), 2012/10/01, Volume 189, Issue 7, p.3631-40, (2012) Read More / View Supplemental Materials
Abstract
Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes.Quintin, J., Saeed S., Martens JH, Giamarellos-Bourboulis EJ, Ifrim DC, Logie C., Jacobs L., Jansen T., Kullberg BJ, Wijmenga C., Joosten LA, Xavier RJ, van der Meer JW, Stunnenberg HG, and Netea MG Cell host & microbe, 2012/08/16, Volume 12, Issue 2, p.223-32, (2012) Read More / View Supplemental Materials
Abstract
Genome-wide siRNA screen for mediators of NF-κB activation.Gewurz, BE, Towfic F., Mar JC, Shinners NP, Takasaki K., Zhao B., Cahir-McFarland ED, Quackenbush J., Xavier RJ, and Kieff E. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/14, Volume 109, Issue 7, p.2467-72, (2012) Read More / View Supplemental Materials
Abstract
Autophagy and the immune system.Kuballa, P., Nolte WM, Castoreno AB, and Xavier RJ Annual review of immunology, 2012/01/01, Volume 30, p.611-46, (2012) Read More / View Supplemental Materials
Abstract
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.Papa, E., Docktor M., Smillie C., Weber S., Preheim SP, Gevers D., Giannoukos G., Ciulla D., Tabbaa D., Ingram J., Schauer DB, Ward DV, Korzenik JR, Xavier RJ, Bousvaros A., and Alm EJ PloS one, 2012/01/01, Volume 7, Issue 6, p.e39242, (2012) Read More / View Supplemental Materials
Abstract
2011
Image-based genome-wide siRNA screen identifies selective autophagy factors.Orvedahl, A., Sumpter R Jr, Xiao G., Ng A., Zou Z., Tang Y., Narimatsu M., Gilpin C., Sun Q., Roth M., Forst CV, Wrana JL, Zhang YE, Luby-Phelps K., Xavier RJ, Xie Y., and Levine B. Nature, 2011/12/01, Volume 480, Issue 7375, p.113-7, (2011) Read More / View Supplemental Materials
Abstract
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.Rivas, MA, Beaudoin M., Gardet A., Stevens C., Sharma Y., Zhang CK, Boucher G., Ripke S., Ellinghaus D., Burtt N., Fennell T., Kirby A., Latiano A., Goyette P., Green T., Halfvarson J., Haritunians T., Korn JM, Kuruvilla F., Lagacé C., et al. Nature genetics, 2011/10/09, Volume 43, Issue 11, p.1066-73, (2011) Read More / View Supplemental Materials
Abstract
Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity.Ng, A., and Xavier RJ Autophagy, 2011/09/01, Volume 7, Issue 9, p.1082-4, (2011) Read More / View Supplemental Materials
Abstract
Genetics and pathogenesis of inflammatory bowel disease.Khor, B., Gardet A., and Xavier RJ Nature, 2011/06/15, Volume 474, Issue 7351, p.307-17, (2011) Read More / View Supplemental Materials
Abstract
Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3.Heath, RJ, Leong JM, Visegrády B., Machesky LM, and Xavier RJ PLoS pathogens, 2011/04/01, Volume 7, Issue 4, p.e1001332, (2011) Read More / View Supplemental Materials
Abstract
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.Rossin, EJ, Lage K., Raychaudhuri S., Xavier RJ, Tatar D., Benita Y., International Inflammatory Bowel Disease Genetics Constortium, Cotsapas C., and Daly M. J. PLoS genetics, 2011/01/13, Volume 7, Issue 1, p.e1001273, (2011) Read More / View Supplemental Materials
Abstract
2010
LRRK2 is involved in the IFN-gamma response and host response to pathogens.Gardet, A., Benita Y., Li C., Sands BE, Ballester I., Stevens C., Korzenik JR, Rioux JD, Daly M. J., Xavier RJ, and Podolsky DK Journal of immunology (Baltimore, Md. : 1950), 2010/11/01, Volume 185, Issue 9, p.5577-85, (2010) Read More / View Supplemental Materials
Abstract
2009
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.Raychaudhuri, S., Plenge RM, Rossin EJ, Ng AC, International Schizophrenia Consortium, Purcell SM, Sklar P., Scolnick EM, Xavier RJ, Altshuler D., and Daly M. J. PLoS genetics, 2009/06/01, Volume 5, Issue 6, p.e1000534, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-18 of 18 Results