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  • Showing 1-8 of 8 Results
2016
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.Rivas, MA, Graham D., Sulem P., Stevens C., Desch AN, Goyette P., Gudbjartsson D., Jonsdottir I., Thorsteinsdottir U., Degenhardt F., Mucha S., Kurki MI, Li D., D'Amato M., Annese V., Vermeire S., Weersma RK, Halfvarson J., Paavola-Sakki P., Lappalainen M., et al. Nature communications, 2016/08/09, Volume 7, p.12342, (2016) Read More / View Supplemental Materials
Abstract
A pleiotropic missense variant in SLC39A8 is associated with Crohn's disease and human gut microbiome composition.Li, D., Achkar JP, Haritunians T., Jacobs JP, Hui KY, D'Amato M., Brand S., Radford-Smith G., Halfvarson J., Niess JH, Kugathasan S., Büning C., Schumm LP, Klei L., Ananthakrishnan A., Aumais G., Baidoo L., Dubinsky M., Fiocchi C., Glas J., et al. Gastroenterology, 2016/08/01, (2016) Read More / View Supplemental Materials
Abstract
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF.Chuang, LS, Villaverde N., Hui KY, Mortha A., Rahman A., Levine AP, Haritunians T., Ng SM, Zhang W., Hsu NY, Facey JA, Luong T., Fernandez-Hernandez H., Li D., Rivas M., Schiff ER, Gusev A., Schumm LP, Bowen BM, Sharma Y., et al. Gastroenterology, 2016/07/01, (2016) Read More / View Supplemental Materials
Abstract
2015
Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis.Kevans, D., Tyler AD, Holm K., Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B., Gevers D., Hov JR, and Silverberg MS Journal of Crohn's & colitis, 2015/11/02, (2015) Read More / View Supplemental Materials
Abstract
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.Cleynen, I., Boucher G., Jostins L., Schumm LP, Zeissig S., Ahmad T., Andersen V., Andrews JM, Annese V., Brand S., Brant SR, Cho JH, Daly M. J., Dubinsky M., Duerr RH, Ferguson LR, Franke A., Gearry RB, Goyette P., Hakonarson H., et al. Lancet (London, England), 2015/10/16, (2015) Read More / View Supplemental Materials
Abstract
Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease.Morgan, XC, Kabakchiev B., Waldron L., Tyler AD, Tickle TL, Milgrom R., Stempak JM, Gevers D., Xavier RJ, Silverberg MS, and Huttenhower C. Genome biology, 2015/04/08, Volume 16, Issue 1, p.67, (2015) Read More / View Supplemental Materials
Abstract
2014
Complex host genetics influence the microbiome in inflammatory bowel disease.Knights, D., Silverberg MS, Weersma RK, Gevers D., Dijkstra G., Huang H., Tyler AD, van Sommeren S., Imhann F., Stempak JM, Huang H., Vangay P., Al-Ghalith GA, Russell C., Sauk J., Knight J., Daly M. J., Huttenhower C., and Xavier RJ Genome medicine, 2014/01/01, Volume 6, Issue 12, p.107, (2014) Read More / View Supplemental Materials
Abstract
2011
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.Rivas, MA, Beaudoin M., Gardet A., Stevens C., Sharma Y., Zhang CK, Boucher G., Ripke S., Ellinghaus D., Burtt N., Fennell T., Kirby A., Latiano A., Goyette P., Green T., Halfvarson J., Haritunians T., Korn JM, Kuruvilla F., Lagacé C., et al. Nature genetics, 2011/10/09, Volume 43, Issue 11, p.1066-73, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-8 of 8 Results