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  • Showing 1-8 of 8 Results
2016
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Ehret, GB, Ferreira T., Chasman DI, Jackson AU, Schmidt EM, Johnson T., Thorleifsson G., Luan J., Donnelly LA, Kanoni S., Petersen AK, Pihur V., Strawbridge RJ, Shungin D., Hughes MF, Meirelles O., Kaakinen M., Bouatia-Naji N., Kristiansson K., Shah S., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.Liu, C., Kraja AT, Smith JA, Brody JA, Franceschini N., Bis JC, Rice K., Morrison AC, Lu Y., Weiss S., Guo X., Palmas W., Martin LW, Chen YI, Surendran P., Drenos F., Cook JP, Auer PL, Chu AY, Giri A., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.Han, B., Pouget JG, Slowikowski K., Stahl E., Lee CH, Diogo D., Hu X., Park YR, Kim E., Gregersen PK, Dahlqvist SR, Worthington J., Martin J., Eyre S., Klareskog L., Huizinga T., Chen WM, Onengut-Gumuscu S., Rich SS, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, et al. Nature genetics, 2016/05/16, (2016) Read More / View Supplemental Materials
Abstract
Systematic functional interrogation of rare cancer variants identifies oncogenic alleles.Kim, E., Ilic N., Shrestha Y., Zou L., Kamburov A., Zhu C., Yang X., Lubonja R., Tran N., Nguyen C., Lawrence MS, Piccioni F., Bagul M., Doench JG, Chouinard CR, Wu X., Hogstrom L., Natoli T., Tamayo P., Horn H., et al. Cancer discovery, 2016/05/04, (2016) Read More / View Supplemental Materials
Abstract
2015
Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling.Kang, HB, Fan J., Lin R., Elf S., Ji Q., Zhao L., Jin L., Seo JH, Shan C., Arbiser JL, Cohen C., Brat D., Miziorko HM, Kim E., Abdel-Wahab O., Merghoub T., Fröhling S., Scholl C., Tamayo P., Barbie DA, et al. Molecular cell, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
2013
TRAF2 is an NF-κB-activating oncogene in epithelial cancers.Shen, RR, Zhou AY, Kim E., O'Connell JT, Hagerstrand D., Beroukhim R., and Hahn WC Oncogene, 2013/12/23, (2013) Read More / View Supplemental Materials
Abstract
Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
Abstract
IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex.Zhou, AY, Shen RR, Kim E., Lock YJ, Xu M., Chen ZJ, and Hahn WC Cell reports, 2013/03/28, Volume 3, Issue 3, p.724-33, (2013) Read More / View Supplemental Materials
Abstract
  • Showing 1-8 of 8 Results