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  • Showing 1-12 of 12 Results
2016
Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis.Okada, Y., Suzuki A., Ikari K., Terao C., Kochi Y., Ohmura K., Higasa K., Akiyama M., Ashikawa K., Kanai M., Hirata J., Suita N., Teo YY, Xu H., Bae SC, Takahashi A., Momozawa Y., Matsuda K., Momohara S., Taniguchi A., et al. American journal of human genetics, 2016/08/04, Volume 99, Issue 2, p.366-74, (2016) Read More / View Supplemental Materials
Abstract
Genomic copy number dictates a gene-independent cell response to CRISPR-Cas9 targeting.Aguirre, AJ, Meyers RM, Weir BA, Vazquez F., Zhang CZ, Ben-David U., Cook A., Ha G., Harrington WF, Doshi MB, Kost-Alimova M., Gill S., Xu H., Ali LD, Jiang G., Pantel S., Lee Y., Goodale A., Cherniack AD, Oh C., et al. Cancer discovery, 2016/06/03, (2016) Read More / View Supplemental Materials
Abstract
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Klionsky, DJ, Abdelmohsen K., Abe A., Abedin MJ, Abeliovich H., Acevedo Arozena A., Adachi H., Adams CM, Adams PD, Adeli K., Adhihetty PJ, Adler SG, Agam G., Agarwal R., Aghi MK, Agnello M., Agostinis P., Aguilar PV, Aguirre-Ghiso J., Airoldi EM, et al. Autophagy, 2016/01/02, Volume 12, Issue 1, p.1-222, (2016) Read More / View Supplemental Materials
2015
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR.Li, W., Köster J., Xu H., Chen CH, Xiao T., Liu JS, Brown M., and Liu XS Genome biology, 2015/12/16, Volume 16, Issue 1, p.281, (2015) Read More / View Supplemental Materials
Abstract
Partitioning heritability by functional annotation using genome-wide association summary statistics.Finucane, HK, Bulik-Sullivan B., Gusev A., Trynka G., Reshef Y., Loh PR, Anttila V., Xu H., Zang C., Farh K., Ripke S., Day FR, ReproGen Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, RACI Consortium, Purcell S., Stahl E., Lindstrom S., Perry JR, Okada Y., et al. Nature genetics, 2015/09/28, (2015) Read More / View Supplemental Materials
Abstract
Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.Trynka, G., Westra HJ, Slowikowski K., Hu X., Xu H., Stranger BE, Klein RJ, Han B., and Raychaudhuri S. American journal of human genetics, 2015/07/02, Volume 97, Issue 1, p.139-52, (2015) Read More / View Supplemental Materials
Abstract
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Chen, CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N., Eng R., Doench JG, Xu H., Chu SH, Qi J., Wang X., Delaney C., Bernt KM, Root DE, Hahn WC, Bradner JE, and Armstrong SA Nature medicine, 2015/03/30, (2015) Read More / View Supplemental Materials
Abstract
2014
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.Gusev, A., Lee SH, Trynka G., Finucane H., Vilhjálmsson BJ, Xu H., Zang C., Ripke S., Bulik-Sullivan B., Stahl E., Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M., Pasaniuc B., Sullivan PF, Neale BM, et al. American journal of human genetics, 2014/11/06, Volume 95, Issue 5, p.535-52, (2014) Read More / View Supplemental Materials
Abstract
Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.Okada, Y., Kim K., Han B., Pillai NE, Ong RT, Saw WY, Luo M., Jiang L., Yin J., Bang SY, Lee HS, Brown MA, Bae SC, Xu H., Teo YY, de Bakker PI, and Raychaudhuri S. Human molecular genetics, 2014/07/28, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Chromatin marks identify critical cell types for fine mapping complex trait variants.Trynka, G., Sandor C., Han B., Xu H., Stranger BE, Liu XS, and Raychaudhuri S. Nature genetics, 2013/02/01, Volume 45, Issue 2, p.124-30, (2013) Read More / View Supplemental Materials
Abstract
2012
Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahydroquinoline Library.Gerard, B., O'Shea MW, Donckele E., Kesavan S., Akella LB, Xu H., Jacobsen EN, and Marcaurelle LA ACS combinatorial science, 2012/10/22, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-12 of 12 Results