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2015
Integrative clinical genomics of advanced prostate cancer.Robinson, D., Van Allen EM, Wu YM, Schultz N., Lonigro RJ, Mosquera JM, Montgomery B., Taplin ME, Pritchard CC, Attard G., Beltran H., Abida W., Bradley RK, Vinson J., Cao X., Vats P., Kunju LP, Hussain M., Feng FY, Tomlins SA, et al. Cell, 2015/05/21, Volume 161, Issue 5, p.1215-28, (2015) Read More / View Supplemental Materials
Abstract
Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.Ahronian, LG, Sennott EM, Van Allen EM, Wagle N., Kwak EL, Faris JE, Godfrey JT, Nishimura K., Lynch KD, Mermel CH, Lockerman EL, Kalsy A., Gurski JM Jr, Bahl S., Anderka K., Green LM, Lennon NJ, Huynh TG, Mino-Kenudson M., Getz G., et al. Cancer discovery, 2015/04/01, Volume 5, Issue 4, p.358-67, (2015) Read More / View Supplemental Materials
Abstract
PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration Resistant Prostate Cancer, is a Mediator of Resistance to Androgen Deprivation Therapy.Hsieh, CL, Botta G., Gao S., Li T., Van Allen EM, Treacy DJ, Cai C., He HH, Sweeney CJ, Brown M., Balk SP, Nelson PS, Garraway LA, and Kantoff PW Cancer research, 2015/03/25, (2015) Read More / View Supplemental Materials
Abstract
A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer.Wilson, FH, Johannessen CM, Piccioni F., Tamayo P., Kim JW, Van Allen EM, Corsello SM, Capelletti M., Calles A., Butaney M., Sharifnia T., Gabriel SB, Mesirov J. P., Hahn WC, Engelman JA, Meyerson M., Root DE, Jänne PA, and Garraway LA Cancer cell, 2015/03/09, Volume 27, Issue 3, p.397-408, (2015) Read More / View Supplemental Materials
Abstract
2014
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.Perry, JA, Kiezun A., Tonzi P., Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E., Pedamallu CS, Helman E., Taylor-Weiner A., McKenna A., Deluca DS, Lawrence MS, Ambrogio L., Sougnez C., Sivachenko A., Walensky LD, Wagle N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/12/15, (2014) Read More / View Supplemental Materials
Abstract
Response and acquired resistance to everolimus in anaplastic thyroid cancer.Wagle, N., Grabiner BC, Van Allen EM, Amin-Mansour A., Taylor-Weiner A., Rosenberg M., Gray N., Barletta JA, Guo Y., Swanson SJ, Ruan DT, Hanna GJ, Haddad RI, Getz G., Kwiatkowski DJ, Carter SL, Sabatini DM, Jänne PA, Garraway LA, and Lorch JH The New England journal of medicine, 2014/10/09, Volume 371, Issue 15, p.1426-33, (2014) Read More / View Supplemental Materials
Abstract
Assessing the clinical utility of cancer genomic and proteomic data across tumor types.Yuan, Y., Van Allen EM, Omberg L., Wagle N., Amin-Mansour A., Sokolov A., Byers LA, Xu Y., Hess KR, Diao L., Han L., Huang X., Lawrence MS, Weinstein J. N., Stuart JM, Mills GB, Garraway LA, Margolin AA, Getz G., and Liang H. Nature biotechnology, 2014/07/01, Volume 32, Issue 7, p.644-52, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.Van Allen, EM, Wagle N., Stojanov P., Perrin DL, Cibulskis K., Marlow S., Jane-Valbuena J., Friedrich DC, Kryukov G., Carter SL, McKenna A., Sivachenko A., Rosenberg M., Kiezun A., Voet D., Lawrence M., Lichtenstein LT, Gentry JG, Huang FW, Fostel J., et al. Nature medicine, 2014/06/01, Volume 20, Issue 6, p.682-8, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.Lohr, JG, Adalsteinsson VA, Cibulskis K., Choudhury AD, Rosenberg M., Cruz-Gordillo P., Francis JM, Zhang CZ, Shalek AK, Satija R., Trombetta JJ, Lu D., Tallapragada N., Tahirova N., Kim S., Blumenstiel B., Sougnez C., Lowe A., Wong B., Auclair D., et al. Nature biotechnology, 2014/05/01, Volume 32, Issue 5, p.479-84, (2014) Read More / View Supplemental Materials
Abstract
Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib.Wagle, N., Grabiner BC, Van Allen EM, Hodis E., Jacobus S., Choueiri TK, Gandhi L., Taplin ME, Stack EC, Signoretti S., Loda M., Shapiro GI, Sabatini DM, Lander E. S., Gabriel SB, Kantoff PW, Garraway LA, and Rosenberg JE Cancer discovery, 2014/03/27, (2014) Read More / View Supplemental Materials
Abstract
2013
Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy.Van Allen, EM, Foye A., Wagle N., Kim W., Carter SL, McKenna A., Simko JP, Garraway LA, and Febbo PG Prostate cancer and prostatic diseases, 2013/12/24, (2013) Read More / View Supplemental Materials
Abstract
Clinical Analysis and Interpretation of Cancer Genome Data.Van Allen, EM, Wagle N., and Levy MA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013/04/15, (2013) Read More / View Supplemental Materials
Abstract
2012
Moving toward personalized medicine in castration-resistant prostate cancer.Van Allen, EM, and Pomerantz M. The Urologic clinics of North America, 2012/11/01, Volume 39, Issue 4, p.483-90, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-13 of 13 Results