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  • Showing 1-15 of 15 Results
2016
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.Campbell, JD, Alexandrov A., Kim J., Wala J., Berger AH, Pedamallu CS, Shukla SA, Guo G., Brooks AN, Murray BA, Imielinski M., Hu X., Ling S., Akbani R., Rosenberg M., Cibulskis C., Ramachandran A., Collisson EA, Kwiatkowski DJ, Lawrence MS, et al. Nature genetics, 2016/05/09, (2016) Read More / View Supplemental Materials
Abstract
Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.Giannakis, M., Mu XJ, Shukla SA, Qian ZR, Cohen O., Nishihara R., Bahl S., Cao Y., Amin-Mansour A., Yamauchi M., Sukawa Y., Stewart C., Rosenberg M., Mima K., Inamura K., Nosho K., Nowak JA, Lawrence MS, Giovannucci EL, Chan AT, et al. Cell reports, 2016/04/14, (2016) Read More / View Supplemental Materials
Abstract
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.McGranahan, N., Furness AJ, Rosenthal R., Ramskov S., Lyngaa R., Saini SK, Jamal-Hanjani M., Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S., Murugaesu N., Mitter R., Akarca AU, Linares J., Marafioti T., Henry JY, Van Allen EM, Miao D., et al. Science (New York, N.Y.), 2016/03/03, (2016) Read More / View Supplemental Materials
Abstract
Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.Strickland, KC, Howitt BE, Shukla SA, Rodig S., Ritterhouse LL, Liu JF, Garber JE, Chowdhury D., Wu CJ, D'Andrea AD, Matulonis UA, and Konstantinopoulos PA Oncotarget, 2016/02/09, (2016) Read More / View Supplemental Materials
Abstract
Neoepitopes and CD3-Positive and CD8-Positive Cells in Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers-Reply.Howitt, BE, Shukla SA, and Konstantinopoulos PA JAMA oncology, 2016/01/01, Volume 2, Issue 1, p.141-2, (2016) Read More / View Supplemental Materials
2015
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.Van Allen, EM, Miao D., Schilling B., Shukla SA, Blank C., Zimmer L., Sucker A., Hillen U., Foppen MH, Goldinger SM, Utikal J., Hassel JC, Weide B., Kaehler KC, Loquai C., Mohr P., Gutzmer R., Dummer R., Gabriel S., Wu CJ, et al. Science (New York, N.Y.), 2015/10/09, Volume 350, Issue 6257, p.207-11, (2015) Read More / View Supplemental Materials
Abstract
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes.Shukla, SA, Rooney MS, Rajasagi M., Tiao G., Dixon PM, Lawrence MS, Lane WJ, Steelman S., Sougnez C., Cibulskis K., Kiezun A., Hacohen N., Brusic V., Wu CJ, and Getz G. Nature biotechnology, 2015/09/15, (2015) Read More / View Supplemental Materials
Abstract
Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1.Howitt, BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S., Stover E., Strickland KC, D'Andrea AD, Wu CJ, Matulonis UA, and Konstantinopoulos PA JAMA oncology, 2015/07/09, (2015) Read More / View Supplemental Materials
Abstract
Molecular and genetic properties of tumors associated with local immune cytolytic activity.Rooney, MS, Shukla SA, Wu CJ, Getz G., and Hacohen N. Cell, 2015/01/15, Volume 160, Issue 1-2, p.48-61, (2015) Read More / View Supplemental Materials
Abstract
2014
The Genomic Landscape of Pediatric Ewing Sarcoma.Crompton, BD, Stewart C., Taylor-Weiner A., Alexe G., Kurek KC, Calicchio ML, Kiezun A., Carter SL, Shukla SA, Mehta SS, Thorner AR, de Torres C., Lavarino C., Sunol M., McKenna A., Sivachenko A., Cibulskis K., Lawrence MS, Stojanov P., Rosenberg M., et al. Cancer discovery, 2014/09/03, (2014) Read More / View Supplemental Materials
Abstract
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia.Rajasagi, M., Shukla SA, Fritsch EF, Keskin DB, Deluca D., Carmona E., Zhang W., Sougnez C., Cibulskis K., Sidney J., Stevenson K., Ritz J., Neuberg D., Brusic V., Gabriel S., Lander E. S., Getz G., Hacohen N., and Wu CJ Blood, 2014/06/02, (2014) Read More / View Supplemental Materials
Abstract
Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.Wang, L., Shalek AK, Lawrence M., Ding R., Gaublomme JT, Pochet N., Stojanov P., Sougnez C., Shukla SA, Stevenson KE, Zhang W., Wong J., Sievers QL, Macdonald BT, Vartanov AR, Goldstein NR, Neuberg D., He X., Lander E., Hacohen N., et al. Blood, 2014/04/28, (2014) Read More / View Supplemental Materials
Abstract
2013
The somatic genomic landscape of glioblastoma.Brennan, CW, Verhaak RG, McKenna A., Campos B., Noushmehr H., Salama SR, Zheng S., Chakravarty D., Sanborn JZ, Berman SH, Beroukhim R., Bernard B., Wu CJ, Genovese G., Shmulevich I., Barnholtz-Sloan J., Zou L., Vegesna R., Shukla SA, Ciriello G., et al. Cell, 2013/10/10, Volume 155, Issue 2, p.462-77, (2013) Read More / View Supplemental Materials
Abstract
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.Landau, DA, Carter SL, Stojanov P., McKenna A., Stevenson K., Lawrence MS, Sougnez C., Stewart C., Sivachenko A., Wang L., Wan Y., Zhang W., Shukla SA, Vartanov A., Fernandes SM, Saksena G., Cibulskis K., Tesar B., Gabriel S., Hacohen N., et al. Cell, 2013/02/14, Volume 152, Issue 4, p.714-26, (2013) Read More / View Supplemental Materials
Abstract
2012
Integrative functional genomics identifies RINT1 as a novel GBM oncogene.Quayle, SN, Chheda MG, Shukla SA, Wiedemeyer R., Tamayo P., Dewan RW, Zhuang L., Huang-Hobbs E., Haidar S., Xiao Y., Ligon KL, Hahn WC, and Chin L. Neuro-oncology, 2012/10/16, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-15 of 15 Results