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  • Showing 1-21 of 21 Results
2014
RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites.Engreitz, JM, Sirokman K., McDonel P., Shishkin AA, Surka C., Russell P., Grossman SR, Chow AY, Guttman M., and Lander E. S. Cell, 2014/09/25, Volume 159, Issue 1, p.188-99, (2014) Read More / View Supplemental Materials
Abstract
RNA Function. RNA and dynamic nuclear organization.Rinn, J., and Guttman M. Science (New York, N.Y.), 2014/09/12, Volume 345, Issue 6202, p.1240-1, (2014) Read More / View Supplemental Materials
Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA.Schwartz, S., Bernstein DA, Mumbach MR, Jovanovic M., Herbst RH, León-Ricardo BX, Engreitz JM, Guttman M., Satija R., Lander E. S., Fink G., and Regev A. Cell, 2014/09/10, (2014) Read More / View Supplemental Materials
Abstract
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre.Hacisuleyman, E., Goff LA, Trapnell C., Williams A., Henao-Mejia J., Sun L., McClanahan P., Hendrickson DG, Sauvageau M., Kelley DR, Morse M., Engreitz J., Lander E. S., Guttman M., Lodish HF, Flavell R., Raj A., and Rinn JL Nature structural & molecular biology, 2014/02/01, Volume 21, Issue 2, p.198-206, (2014) Read More / View Supplemental Materials
Abstract
2013
The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome.Engreitz, JM, Pandya-Jones A., McDonel P., Shishkin A., Sirokman K., Surka C., Kadri S., Xing J., Goren A., Lander E. S., Plath K., and Guttman M. Science (New York, N.Y.), 2013/07/04, (2013) Read More / View Supplemental Materials
Abstract
Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins.Guttman, M., Russell P., Ingolia NT, Weissman JS, and Lander E. S. Cell, 2013/07/03, Volume 154, Issue 1, p.240-51, (2013) Read More / View Supplemental Materials
Abstract
Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.Gifford, CA, Ziller MJ, Gu H., Trapnell C., Donaghey J., Tsankov A., Shalek AK, Kelley DR, Shishkin AA, Issner R., Zhang X., Coyne M., Fostel JL, Holmes L., Meldrim J., Guttman M., Epstein C., Park H., Kohlbacher O., Rinn J., et al. Cell, 2013/05/23, Volume 153, Issue 5, p.1149-63, (2013) Read More / View Supplemental Materials
Abstract
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.Kirby, A., Gnirke A., Jaffe DB, Barešová V., Pochet N., Blumenstiel B., Ye C., Aird D., Stevens C., Robinson JT, Cabili MN, Gat-Viks I., Kelliher E., Daza R., DeFelice M., Hůlková H., Sovová J., Vylet'al P., Antignac C., Guttman M., et al. Nature genetics, 2013/03/01, Volume 45, Issue 3, p.299-303, (2013) Read More / View Supplemental Materials
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2012
A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals.Garber, M., Yosef N., Goren A., Raychowdhury R., Thielke A., Guttman M., Robinson J., Minie B., Chevrier N., Itzhaki Z., Blecher-Gonen R., Bornstein C., Amann-Zalcenstein D., Weiner A., Friedrich D., Meldrim J., Ram O., Cheng C., Gnirke A., Fisher S., et al. Molecular cell, 2012/09/14, Volume 47, Issue 5, p.810-22, (2012) Read More / View Supplemental Materials
Abstract
Modular regulatory principles of large non-coding RNAs.Guttman, M., and Rinn JL Nature, 2012/02/15, Volume 482, Issue 7385, p.339-46, (2012) Read More / View Supplemental Materials
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2011
A high-resolution map of human evolutionary constraint using 29 mammals.Lindblad-Toh, K., Garber M., Zuk O., Lin MF, Parker BJ, Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward LD, Lowe CB, Holloway AK, Clamp M., Gnerre S., Alföldi J., Beal K., Chang J., Clawson H., Cuff J., et al. Nature, 2011/10/12, Volume 478, Issue 7370, p.476-82, (2011) Read More / View Supplemental Materials
Abstract
lincRNAs act in the circuitry controlling pluripotency and differentiation.Guttman, M., Donaghey J., Carey BW, Garber M., Grenier JK, Munson G., Young G., Lucas AB, Ach R., Bruhn L., Yang X., Amit I., Meissner A., Regev A., Rinn JL, Root DE, and Lander E. S. Nature, 2011/08/28, Volume 477, Issue 7364, p.295-300, (2011) Read More / View Supplemental Materials
Abstract
Computational methods for transcriptome annotation and quantification using RNA-seq.Garber, M., Grabherr MG, Guttman M., and Trapnell C. Nature methods, 2011/06/01, Volume 8, Issue 6, p.469-77, (2011) Read More / View Supplemental Materials
Abstract
Integrative genomics viewer.Robinson, JT, Thorvaldsdóttir H., Winckler W., Guttman M., Lander E. S., Getz G., and Mesirov J. P. Nature biotechnology, 2011/01/01, Volume 29, Issue 1, p.24-6, (2011) Read More / View Supplemental Materials
2010
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.Loewer, S., Cabili MN, Guttman M., Loh YH, Thomas K., Park IH, Garber M., Curran M., Onder T., Agarwal S., Manos PD, Datta S., Lander E. S., Schlaeger TM, Daley GQ, and Rinn JL Nature genetics, 2010/12/01, Volume 42, Issue 12, p.1113-7, (2010) Read More / View Supplemental Materials
Abstract
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response.Huarte, M., Guttman M., Feldser D., Garber M., Koziol MJ, Kenzelmann-Broz D., Khalil AM, Zuk O., Amit I., Rabani M., Attardi LD, Regev A., Lander E. S., Jacks T., and Rinn JL Cell, 2010/08/06, Volume 142, Issue 3, p.409-19, (2010) Read More / View Supplemental Materials
Abstract
Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs.Guttman, M., Garber M., Levin JZ, Donaghey J., Robinson J., Adiconis X., Fan L., Koziol MJ, Gnirke A., Nusbaum C., Rinn JL, Lander E. S., and Regev A. Nature biotechnology, 2010/05/01, Volume 28, Issue 5, p.503-10, (2010) Read More / View Supplemental Materials
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2009
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses.Amit, I., Garber M., Chevrier N., Leite AP, Donner Y., Eisenhaure T., Guttman M., Grenier JK, Li W., Zuk O., Schubert LA, Birditt B., Shay T., Goren A., Zhang X., Smith Z., Deering R., McDonald RC, Cabili M., Bernstein BE, et al. Science (New York, N.Y.), 2009/10/09, Volume 326, Issue 5950, p.257-63, (2009) Read More / View Supplemental Materials
Abstract
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression.Khalil, AM, Guttman M., Huarte M., Garber M., Raj A., Rivea Morales D., Thomas K., Presser A., Bernstein BE, van Oudenaarden A., Regev A., Lander E. S., and Rinn JL Proceedings of the National Academy of Sciences of the United States of America, 2009/07/14, Volume 106, Issue 28, p.11667-72, (2009) Read More / View Supplemental Materials
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Identifying novel constrained elements by exploiting biased substitution patterns.Garber, M., Guttman M., Clamp M., Zody MC, Friedman N., and Xie X. Bioinformatics (Oxford, England), 2009/06/15, Volume 25, Issue 12, p.i54-62, (2009) Read More / View Supplemental Materials
Abstract
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.Guttman, M., Amit I., Garber M., French C., Lin MF, Feldser D., Huarte M., Zuk O., Carey BW, Cassady JP, Cabili MN, Jaenisch R., Mikkelsen TS, Jacks T., Hacohen N., Bernstein BE, Kellis M., Regev A., Rinn JL, and Lander E. S. Nature, 2009/03/12, Volume 458, Issue 7235, p.223-7, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-21 of 21 Results