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2016
52 Genetic Loci Influencing Myocardial Mass.van der Harst, P., van Setten J., Verweij N., Vogler G., Franke L., Maurano MT, Wang X., Mateo Leach I., Eijgelsheim M., Sotoodehnia N., Hayward C., Sorice R., Meirelles O., Lyytikäinen LP, Polašek O., Tanaka T., Arking DE, Ulivi S., Trompet S., Müller-Nurasyid M., et al. Journal of the American College of Cardiology, 2016/09/27, Volume 68, Issue 13, p.1435-48, (2016) Read More / View Supplemental Materials
Abstract
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Ehret, GB, Ferreira T., Chasman DI, Jackson AU, Schmidt EM, Johnson T., Thorleifsson G., Luan J., Donnelly LA, Kanoni S., Petersen AK, Pihur V., Strawbridge RJ, Shungin D., Hughes MF, Meirelles O., Kaakinen M., Bouatia-Naji N., Kristiansson K., Shah S., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.van Rheenen, W., Shatunov A., Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, Võsa U., de Jong S., Robinson MR, Yang J., Fogh I., van Doormaal PT, Tazelaar GH, Koppers M., Blokhuis AM, Sproviero W., Jones AR, Kenna KP, van Eijk KR, et al. Nature genetics, 2016/07/25, (2016) Read More / View Supplemental Materials
Abstract
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.Gormley, P., Anttila V., Winsvold BS, Palta P., Esko T., Pers TH, Farh KH, Cuenca-Leon E., Muona M., Furlotte NA, Kurth T., Ingason A., McMahon G., Ligthart L., Terwindt GM, Kallela M., Freilinger TM, Ran C., Gordon SG, Stam AH, et al. Nature genetics, 2016/06/20, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide association study identifies 74 loci associated with educational attainment.Okbay, A., Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P., Chen GB, Emilsson V., Meddens SF, Oskarsson S., Pickrell JK, Thom K., Timshel P., de Vlaming R., Abdellaoui A., Ahluwalia TS, Bacelis J., Baumbach C., Bjornsdottir G., et al. Nature, 2016/05/11, Volume 533, Issue 7604, p.539-42, (2016) Read More / View Supplemental Materials
Abstract
Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes.Pers, TH, Timshel P., Ripke S., Lent S., Sullivan PF, O'Donovan MC, Franke L., Hirschhorn JN, and Schizophrenia Working Group of the Psychiatric Genomics Consortium Human molecular genetics, 2016/03/15, Volume 25, Issue 6, p.1247-54, (2016) Read More / View Supplemental Materials
Abstract
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.Ellinghaus, D., Jostins L., Spain SL, Cortes A., Bethune J., Han B., Park YR, Raychaudhuri S., Pouget JG, Hübenthal M., Folseraas T., Wang Y., Esko T., Metspalu A., Westra HJ, Franke L., Pers TH, Weersma RK, Collij V., D'Amato M., et al. Nature genetics, 2016/03/14, (2016) Read More / View Supplemental Materials
Abstract
Twenty-eight genetic loci associated with ST-T wave amplitudes of the electrocardiogram.Verweij, N., Mateo Leach I., Isaacs A., Arking DE, Bis JC, Pers TH, van den Berg ME, Lyytikäinen LP, Barnett P., Wang X., study LifeLines Cohort, Soliman EZ, van Duijn CM, Kähönen M., van Veldhuisen DJ, Kors JA, Raitakari OT, Silva CT, Lehtimäki T., Hillege HL, et al. Human molecular genetics, 2016/03/08, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.Kilpeläinen, TO, Carli JF, Skowronski AA, Sun Q., Kriebel J., Feitosa MF, Hedman Å. K., Drong AW, Hayes JE, Zhao J., Pers TH, Schick U., Grarup N., Kutalik Z., Trompet S., Mangino M., Kristiansson K., Beekman M., Lyytikäinen LP, Eriksson J., et al. Nature communications, 2016/02/01, Volume 7, p.10494, (2016) Read More / View Supplemental Materials
Abstract
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.Lu, Y., Day FR, Gustafsson S., Buchkovich ML, Na J., Bataille V., Cousminer DL, Dastani Z., Drong AW, Esko T., Evans DM, Falchi M., Feitosa MF, Ferreira T., Hedman Å. K., Haring R., Hysi PG, Iles MM, Justice AE, Kanoni S., et al. Nature communications, 2016/02/01, Volume 7, p.10495, (2016) Read More / View Supplemental Materials
Abstract
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Pattaro, C., Teumer A., Gorski M., Chu AY, Li M., Mijatovic V., Garnaas M., Tin A., Sorice R., Li Y., Taliun D., Olden M., Foster M., Yang Q., Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C., Tayo B., et al. Nature communications, 2016/01/21, Volume 7, p.10023, (2016) Read More / View Supplemental Materials
Abstract
2015
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.Felix, JF, Bradfield JP, Monnereau C., van der Valk RJ, Stergiakouli E., Chesi A., Gaillard R., Feenstra B., Thiering E., Kreiner-Møller E., Mahajan A., Pitkänen N., Joro R., Cavadino A., Huikari V., Franks S., Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Gene-Based Meta-Analysis of Genome-Wide Association Studies Implicates New Loci Involved in Obesity.Hägg, S., Ganna A., van der Laan SW, Esko T., Pers TH, Locke AE, Berndt SI, Justice AE, Kahali B., Siemelink MA, Pasterkamp G., GIANT Consortium, Strachan DP, Speliotes EK, North KE, Loos RJ, Hirschhorn JN, Pawitan Y., and Ingelsson E. Human molecular genetics, 2015/09/16, (2015) Read More / View Supplemental Materials
Abstract
Population genetic differentiation of height and body mass index across Europe.Robinson, MR, Hemani G., Medina-Gomez C., Mezzavilla M., Esko T., Shakhbazov K., Powell JE, Vinkhuyzen A., Berndt SI, Gustafsson S., Justice AE, Kahali B., Locke AE, Pers TH, Vedantam S., Wood AR, van Rheenen W., Andreassen OA, Gasparini P., Metspalu A., et al. Nature genetics, 2015/09/14, (2015) Read More / View Supplemental Materials
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Predicting facial characteristics from complex polygenic variations.Fagertun, J., Wolffhechel K., Pers TH, Nielsen HB, Gudbjartsson D., Stefansson H., Stefansson K., Paulsen RR, and Jarmer H. Forensic science international. Genetics, 2015/08/17, Volume 19, p.263-268, (2015) Read More / View Supplemental Materials
Abstract
Mendelian randomization study of height and risk of colorectal cancer.Thrift, AP, Gong J., Peters U., Chang-Claude J., Rudolph A., Slattery ML, Chan AT, Esko T., Wood AR, Yang J., Vedantam S., Gustafsson S., Pers TH, GIANT Consortium, Baron JA, Bezieau S., Küry S., Ogino S., Berndt SI, Casey G., et al. International journal of epidemiology, 2015/05/20, (2015) Read More / View Supplemental Materials
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The impact of low-frequency and rare variants on lipid levels.Surakka, I., Horikoshi M., Mägi R., Sarin AP, Mahajan A., Lagou V., Marullo L., Ferreira T., Miraglio B., Timonen S., Kettunen J., Pirinen M., Karjalainen J., Thorleifsson G., Hägg S., Hottenga JJ, Isaacs A., Ladenvall C., Beekman M., Esko T., et al. Nature genetics, 2015/05/11, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development.Chan, Y., Salem RM, Hsu YH, McMahon G., Pers TH, Vedantam S., Esko T., Guo MH, Lim ET, GIANT Consortium, Franke L., Smith GD, Strachan DP, and Hirschhorn JN American journal of human genetics, 2015/04/08, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Biological interpretation of genome-wide association studies using predicted gene functions.Pers, TH, Karjalainen JM, Chan Y., Westra HJ, Wood AR, Yang J., Lui JC, Vedantam S., Gustafsson S., Esko T., Frayling T., Speliotes EK, Genetic Investigation of ANthropometric Traits(GIANT) Consortium, Boehnke M., Raychaudhuri S., Fehrmann RS, Hirschhorn JN, and Franke L. Nature communications, 2015/01/19, Volume 6, p.5890, (2015) Read More / View Supplemental Materials
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Gene expression analysis identifies global gene dosage sensitivity in cancer.Fehrmann, RS, Karjalainen JM, Krajewska M., Westra HJ, Maloney D., Simeonov A., Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, Te Meerman GJ, Wijmenga C., van Vugt MA, and Franke L. Nature genetics, 2015/01/12, (2015) Read More / View Supplemental Materials
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Multilocus heterozygosity and coronary heart disease: nested case-control studies in men and women.Mukamal, KJ, Jensen MK, Pers TH, Pai JK, Kraft P., and Rimm EB PloS one, 2015/01/01, Volume 10, Issue 5, p.e0124847, (2015) Read More / View Supplemental Materials
Abstract
2014
SNPsnap: a web-based tool for identification and annotation of matched SNPs.Pers, TH, Timshel P., and Hirschhorn JN Bioinformatics (Oxford, England), 2014/10/13, (2014) Read More / View Supplemental Materials
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Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
A novel common variant in DCST2 is associated with length in early life and height in adulthood.van der Valk, RJ, Kreiner-Møller E., Kooijman MN, Guxens M., Stergiakouli E., Sääf A., Bradfield JP, Geller F., Hayes MG, Cousminer DL, Körner A., Thiering E., Curtin JA, Myhre R., Huikari V., Joro R., Kerkhof M., Warrington NM, Pitkänen N., Ntalla I., et al. Human molecular genetics, 2014/10/03, (2014) Read More / View Supplemental Materials
Abstract
Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.Rietveld, CA, Esko T., Davies G., Pers TH, Turley P., Benyamin B., Chabris CF, Emilsson V., Johnson AD, Lee JJ, de Leeuw C., Marioni RE, Medland SE, Miller MB, Rostapshova O., van der Lee SJ, Vinkhuyzen AA, Amin N., Conley D., Derringer J., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/09/08, (2014) Read More / View Supplemental Materials
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Genome-wide association analyses identify variants in developmental genes associated with hypospadias.Geller, F., Feenstra B., Carstensen L., Pers TH, van Rooij IA, Körberg IB, Choudhry S., Karjalainen JM, Schnack TH, Hollegaard MV, Feitz WF, Roeleveld N., Hougaard DM, Hirschhorn JN, Franke L., Baskin LS, Nordenskjöld A., van der Zanden LF, and Melbye M. Nature genetics, 2014/08/10, (2014) Read More / View Supplemental Materials
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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.Perry, JR, Day F., Elks CE, Sulem P., Thompson DJ, Ferreira T., He C., Chasman DI, Esko T., Thorleifsson G., Albrecht E., Ang WQ, Corre T., Cousminer DL, Feenstra B., Franceschini N., Ganna A., Johnson AD, Kjellqvist S., Lunetta KL, et al. Nature, 2014/07/23, (2014) Read More / View Supplemental Materials
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2013
Concordance of gene expression in human protein complexes reveals tissue specificity and pathology.Börnigen, D., Pers TH, Thorrez L., Huttenhower C., Moreau Y., and Brunak S. Nucleic acids research, 2013/08/05, (2013) Read More / View Supplemental Materials
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MetaRanker 2.0: a web server for prioritization of genetic variation data.Pers, TH, Dworzynski P., Thomas CE, Lage K., and Brunak S. Nucleic acids research, 2013/07/01, Volume 41, Issue W1, p.W104-W108, (2013) Read More / View Supplemental Materials
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2012
Novel Microcephalic Primordial Dwarfism Disorder Associated with Variants in the Centrosomal Protein Ninein.Dauber, A., Lafranchi SH, Maliga Z., Lui JC, Moon JE, McDeed C., Henke K., Zonana J., Kingman GA, Pers TH, Baron J., Rosenfeld RG, Hirschhorn JN, Harris MP, and Hwa V. The Journal of clinical endocrinology and metabolism, 2012/08/29, (2012) Read More / View Supplemental Materials
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  • Showing 1-33 of 33 Results