Recent Broad Publications

Mutational heterogeneity in cancer and the search for new cancer-associated genes.
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Genetic risk variants in African Americans with multiple sclerosis.
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Hopping between Differentiation States in Lung Adenocarcinoma.
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
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The Genome of Anopheles darlingi, the main neotropical malaria vector.
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Scientific Publications

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Filters: Author is Girgis, HS [Clear All Filters]

2013

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling.Plovanich, M., Bogorad RL, Sancak Y., Kamer KJ, Strittmatter L., Li AA, Girgis HS, Kuchimanchi S., De Groot J., Speciner L., Taneja N., Oshea J., Koteliansky V., and Mootha VK PloS one, 2013/01/01, Volume 8, Issue 2, p.e55785, (2013) Read More / View Supplemental Materials

2011

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.Baughman, JM, Perocchi F., Girgis HS, Plovanich M., Belcher-Timme CA, Sancak Y., Bao XR, Strittmatter L., Goldberger O., Bogorad RL, Koteliansky V., and Mootha VK Nature, 2011/06/19, Volume 476, Issue 7360, p.341-5, (2011) Read More / View Supplemental Materials

2010

MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.Perocchi, F., Gohil VM, Girgis HS, Bao XR, McCombs JE, Palmer AE, and Mootha VK Nature, 2010/09/16, Volume 467, Issue 7313, p.291-6, (2010) Read More / View Supplemental Materials