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2012
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.Dockendorff, C., Nagiec MM, Weïwer M., Buhrlage S., Ting A., Nag PP, Germain A., Kim HJ, Youngsaye W., Scherer C., Bennion M., Xue L., Stanton BZ, Lewis TA, Macpherson L., Palmer M., Foley MA, Perez JR, and Schreiber SL ACS medicinal chemistry letters, 2012/10/11, Volume 3, Issue 10, p.808-813, (2012) Read More / View Supplemental Materials
Abstract
Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor.Dockendorff, C., Aisiku O., VerPlank L., Dilks JR, Smith DA, Gunnink SF, Dowal L., Negri J., Palmer M., Macpherson L., Schreiber SL, and Flaumenhaft R. ACS medicinal chemistry letters, 2012/03/08, Volume 3, Issue 3, p.232-237, (2012) Read More / View Supplemental Materials
Abstract
Development of small-molecule probes that selectively kill cells induced to express mutant RAS.Weïwer, M., Bittker JA, Lewis TA, Shimada K., Yang WS, Macpherson L., Dandapani S., Palmer M., Stockwell BR, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/02/15, Volume 22, Issue 4, p.1822-6, (2012) Read More / View Supplemental Materials
Abstract
Chemical Genetic Analysis of Platelet Granule Secretion-Probe 1VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Chemical Genetic Analysis of Platelet Granule Secretion-Probe 2VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Chemical Genetic Analysis of Platelet Granule Secretion-Probe 3VerPlank, L., Dockendorff C., Negri J., Perez JR, Dilks J., Macpherson L., Palmer M., Flaumenhaft R., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of a small molecule that selectively activates alpha-synuclein translational expressionRoss, NT, Metkar SR, Le H., Burbank J., Cahill C., Germain A., Macpherson L., Bittker J., Palmer M., Rogers J., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of a small molecule that selectively inhibits alpha-synuclein translational expressionRoss, NT, Metkar SR, Le H., Burbank J., Cahill C., Germain A., Macpherson L., Bittker J., Palmer M., Rogers J., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 1An, WF, Metkar SR, Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 2An, WF, Metkar SR, Lewis TA, Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit streptokinase expression without suppression of viability in Group A streptococci - Probe 3An, WF, Metkar SR, Youngsaye W., Nag PP, Hartland CL, Barker D., Perez JR, Sun H., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of Small-Molecule Inhibitors of Trypansoma cruzi InfectionCarmody, LC, Germain A., Barker D., Galan-Rodriguez C., Bettiol E., Rodriguez A., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 1Carmody, LC, Germain A., Barker D., Galan-Rodriguez C., Bettiol E., Rodriguez A., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 3Carmody, LC, Germain A., Barker D., Galan-Rodriguez C., Bettiol E., Rodriguez A., Macpherson L., Palmer M., and Schreiber SL, 2012/01/09, (2012) Read More / View Supplemental Materials
Abstract
2011
Identification of small-molecule inhibitors of Trypansoma cruzi replication.Germain, AR, Carmody LC, Dockendorff C., Galan-Rodriguez C., Rodriguez A., Johnston S., Bittker JA, Macpherson L., Dandapani S., Palmer M., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2011/12/01, Volume 21, Issue 23, p.7197-200, (2011) Read More / View Supplemental Materials
Abstract
Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates.Youngsaye, W., Vincent B., Hartland CL, Morgan BJ, Buhrlage SJ, Johnston S., Bittker JA, Macpherson L., Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2011/09/15, Volume 21, Issue 18, p.5502-5, (2011) Read More / View Supplemental Materials
Abstract
2010
Screen for RAS-Selective Lethal Compounds and VDAC LigandsBittker, JA, Weiwer M., Shimada K., Yang WS, Macpherson L., Dandapani S., Munoz B., Palmer M., Stockwell BR, and Schreiber SL, 2010/03/26, (2010) Read More / View Supplemental Materials
Abstract
Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence - Probe 2Hartland, CL, Youngsaye W., Morgan B., Ting A., Nag P., Buhrlage S., Johnston S., Bittker J., Vincent B., Whitesell L., Dandapani S., Macpherson L., Munoz B., Palmer M., Lindquist S., and Schreiber SL, 2010/01/01, (2010) Read More / View Supplemental Materials
Abstract
Identification of Small Molecules that Selectively Inhibit Fluconazole-Resistant Candida Albicans in the Presence of Fluconazole but not in its Absence - Probe 3Hartland, CL, Youngsaye W., Dockendorff C., Johnston S., Bittker J., Vincent B., Whitesell L., Dandapani S., Macpherson L., Munoz B., Palmer M., Lindquist S., and Schreiber SL, 2010/01/01, (2010) Read More / View Supplemental Materials
Abstract
Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 2Bittker, JA, Weiwer M., Lewis T., Shimada K., Yang WS, Macpherson L., Dandapani S., Munoz B., Palmer M., Stockwell BR, and Schreiber SL, 2010/01/01, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-20 of 20 Results