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  • Showing 1-14 of 14 Results
2014
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.Wawer, MJ, Li K., Gustafsdottir SM, Ljosa V., Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E., Taylor B., Grant GB, Hon CS, Duvall JR, Wilson JA, Bittker JA, Dančík V., Narayan R., Subramanian A., Winckler W., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/07/14, (2014) Read More / View Supplemental Materials
Abstract
2013
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.Hartwell, KA, Miller PG, Mukherjee S., Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M., Järås M., Puram R., Dancik V., Al-Shahrour F., Kindler T., Tothova Z., Chattopadhyay S., Hasaka T., Narayan R., Dai M., Huang C., Shterental S., et al. Nature chemical biology, 2013/12/01, Volume 9, Issue 12, p.840-8, (2013) Read More / View Supplemental Materials
Abstract
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.Basu, A., Bodycombe NE, Cheah JH, Price EV, Liu K., Schaefer GI, Ebright RY, Stewart ML, Ito D., Wang S., Bracha AL, Liefeld T., Wawer M., Gilbert JC, Wilson AJ, Stransky N., Kryukov GV, Dancik V., Barretina J., Garraway LA, et al. Cell, 2013/08/29, Volume 154, Issue 5, p.1151-61, (2013) Read More / View Supplemental Materials
Abstract
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.Mulrooney, CA, Lahr DL, Quintin MJ, Youngsaye W., Moccia D., Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P., Bittker JA, Clemons PA, Brudz S., Dandapani S., Duvall JR, Tolliday NJ, and De Souza A. Journal of computer-aided molecular design, 2013/04/13, (2013) Read More / View Supplemental Materials
Abstract
ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans.Youngsaye, W., Hartland CL, Morgan BJ, Ting A., Nag PP, Vincent B., Mosher CA, Bittker JA, Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Beilstein journal of organic chemistry, 2013/01/01, Volume 9, p.1501-7, (2013) Read More / View Supplemental Materials
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2012
Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles.Youngsaye, W., Dockendorff C., Vincent B., Hartland CL, Bittker JA, Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/05/01, Volume 22, Issue 9, p.3362-5, (2012) Read More / View Supplemental Materials
Abstract
High-Throughput RT-PCR for small-molecule screening assays.Bittker, JA Current protocols in chemical biology, 2012/03/01, Volume 4, Issue 1, p.49-63, (2012) Read More / View Supplemental Materials
Abstract
Development of small-molecule probes that selectively kill cells induced to express mutant RAS.Weïwer, M., Bittker JA, Lewis TA, Shimada K., Yang WS, Macpherson L., Dandapani S., Palmer M., Stockwell BR, Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2012/02/15, Volume 22, Issue 4, p.1822-6, (2012) Read More / View Supplemental Materials
Abstract
2011
Identification of small-molecule inhibitors of Trypansoma cruzi replication.Germain, AR, Carmody LC, Dockendorff C., Galan-Rodriguez C., Rodriguez A., Johnston S., Bittker JA, Macpherson L., Dandapani S., Palmer M., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2011/12/01, Volume 21, Issue 23, p.7197-200, (2011) Read More / View Supplemental Materials
Abstract
Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates.Youngsaye, W., Vincent B., Hartland CL, Morgan BJ, Buhrlage SJ, Johnston S., Bittker JA, Macpherson L., Dandapani S., Palmer M., Whitesell L., Lindquist S., Schreiber SL, and Munoz B. Bioorganic & medicinal chemistry letters, 2011/09/15, Volume 21, Issue 18, p.5502-5, (2011) Read More / View Supplemental Materials
Abstract
2010
Small-molecule inducers of insulin expression in pancreatic alpha-cells.Fomina-Yadlin, D., Kubicek S., Walpita D., Dancik V., Hecksher-Sørensen J., Bittker JA, Sharifnia T., Shamji A., Clemons PA, Wagner BK, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2010/08/24, Volume 107, Issue 34, p.15099-104, (2010) Read More / View Supplemental Materials
Abstract
Screen for RAS-Selective Lethal Compounds and VDAC LigandsBittker, JA, Weiwer M., Shimada K., Yang WS, Macpherson L., Dandapani S., Munoz B., Palmer M., Stockwell BR, and Schreiber SL, 2010/03/26, (2010) Read More / View Supplemental Materials
Abstract
Discovery of Inhibitors of Anti-Apoptotic Protein A1Bittker, JA, Weiwer M., Wei G., Germain A., Brown E., Dandapani S., Munoz B., Palmer M., Golub T., and Schreiber SL, 2010/01/01, (2010) Read More / View Supplemental Materials
Abstract
Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 2Bittker, JA, Weiwer M., Lewis T., Shimada K., Yang WS, Macpherson L., Dandapani S., Munoz B., Palmer M., Stockwell BR, and Schreiber SL, 2010/01/01, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-14 of 14 Results