MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors. Birsoy, K. , Wang T. , Possemato R. , Yilmaz OH , Koch CE , Chen WW , Hutchins AW , Gultekin Y. , Peterson TR , Carette JE , Brummelkamp TR , Clish CB , and Sabatini DM Nature genetics, 2012/12/16, Volume 45, Issue 1, p.104-8, (2012)
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Abstract
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake. Yilmaz, OH , Katajisto P. , Lamming DW , Gültekin Y. , Bauer-Rowe KE , Sengupta S. , Birsoy K. , Dursun A. , Yilmaz VO , Selig M. , Nielsen GP , Mino-Kenudson M. , Zukerberg LR , Bhan AK , Deshpande V. , and Sabatini DM Nature, 2012/05/20, (2012)
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Abstract