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2013
Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.Kawate, T., Iwase N., Shimizu M., Stanley SA, Wellington S., Kazyanskaya E., and Hung DT Bioorganic & medicinal chemistry letters, 2013/11/15, Volume 23, Issue 22, p.6052-9, (2013) Read More / View Supplemental Materials
Abstract
Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.Stanley, SA, Kawate T., Iwase N., Shimizu M., Clatworthy AE, Kazyanskaya E., Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S., Aquadro JA, Schmidt Grant S., Rubin EJ, and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2013/07/09, Volume 110, Issue 28, p.11565-70, (2013) Read More / View Supplemental Materials
Abstract
2012
Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening.Stanley, SA, Grant SS, Kawate T., Iwase N., Shimizu M., Wivagg C., Silvis M., Kazyanskaya E., Aquadro J., Golas A., FitzGerald M., Dai H., Zhang L., and Hung DT ACS chemical biology, 2012/05/21, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-3 of 3 Results