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  • Showing 1-7 of 7 Results
2016
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.Hata, AN, Niederst MJ, Archibald HL, Gomez-Caraballo M., Siddiqui FM, Mulvey HE, Maruvka YE, Ji F., Bhang HC, Krishnamurthy Radhakrishna V., Siravegna G., Hu H., Raoof S., Lockerman E., Kalsy A., Lee D., Keating CL, Ruddy DA, Damon LJ, Crystal AS, et al. Nature medicine, 2016/02/01, (2016) Read More / View Supplemental Materials
Abstract
2015
Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.Shaw, AT, Friboulet L., Leshchiner I., Gainor JF, Bergqvist S., Brooun A., Burke BJ, Deng YL, Liu W., Dardaei L., Frias RL, Schultz KR, Logan J., James LP, Smeal T., Timofeevski S., Katayama R., Iafrate AJ, Le L., McTigue M., et al. The New England journal of medicine, 2015/12/23, (2015) Read More / View Supplemental Materials
Abstract
Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.Ahronian, LG, Sennott EM, Van Allen EM, Wagle N., Kwak EL, Faris JE, Godfrey JT, Nishimura K., Lynch KD, Mermel CH, Lockerman EL, Kalsy A., Gurski JM Jr, Bahl S., Anderka K., Green LM, Lennon NJ, Huynh TG, Mino-Kenudson M., Getz G., et al. Cancer discovery, 2015/04/01, Volume 5, Issue 4, p.358-67, (2015) Read More / View Supplemental Materials
Abstract
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer.Niederst, MJ, Sequist LV, Poirier JT, Mermel CH, Lockerman EL, Garcia AR, Katayama R., Costa C., Ross KN, Moran T., Howe E., Fulton LE, Mulvey HE, Bernardo LA, Mohamoud F., Miyoshi N., VanderLaan PA, Costa DB, Jänne PA, Borger DR, et al. Nature communications, 2015/03/11, Volume 6, p.6377, (2015) Read More / View Supplemental Materials
Abstract
A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer.Wilson, FH, Johannessen CM, Piccioni F., Tamayo P., Kim JW, Van Allen EM, Corsello SM, Capelletti M., Calles A., Butaney M., Sharifnia T., Gabriel SB, Mesirov J. P., Hahn WC, Engelman JA, Meyerson M., Root DE, Jänne PA, and Garraway LA Cancer cell, 2015/03/09, Volume 27, Issue 3, p.397-408, (2015) Read More / View Supplemental Materials
Abstract
2014
Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.Zhu, Z., Aref AR, Cohoon TJ, Barbie TU, Imamura Y., Yang S., Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P., Godfrey JT, Qian ZR, Page AN, Maciag K., Chan EM, Silkworth W., Labowsky MT, Rozhansky L., et al. Cancer discovery, 2014/01/20, (2014) Read More / View Supplemental Materials
Abstract
2011
Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers.Cheung, HW, Du J., Boehm JS, He F., Weir BA, Wang X., Butaney M., Sequist LV, Luo B., Engelman JA, Root DE, Meyerson M., Golub T. R., Jänne PA, and Hahn WC Cancer discovery, 2011/12/01, Volume 1, Issue 7, p.608-25, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-7 of 7 Results