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2016
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.Hata, AN, Niederst MJ, Archibald HL, Gomez-Caraballo M., Siddiqui FM, Mulvey HE, Maruvka YE, Ji F., Bhang HC, Krishnamurthy Radhakrishna V., Siravegna G., Hu H., Raoof S., Lockerman E., Kalsy A., Lee D., Keating CL, Ruddy DA, Damon LJ, Crystal AS, et al. Nature medicine, 2016/02/01, (2016) Read More / View Supplemental Materials
Abstract
2015
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer.Niederst, MJ, Sequist LV, Poirier JT, Mermel CH, Lockerman EL, Garcia AR, Katayama R., Costa C., Ross KN, Moran T., Howe E., Fulton LE, Mulvey HE, Bernardo LA, Mohamoud F., Miyoshi N., VanderLaan PA, Costa DB, Jänne PA, Borger DR, et al. Nature communications, 2015/03/11, Volume 6, p.6377, (2015) Read More / View Supplemental Materials
Abstract
2011
Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers.Cheung, HW, Du J., Boehm JS, He F., Weir BA, Wang X., Butaney M., Sequist LV, Luo B., Engelman JA, Root DE, Meyerson M., Golub T. R., Jänne PA, and Hahn WC Cancer discovery, 2011/12/01, Volume 1, Issue 7, p.608-25, (2011) Read More / View Supplemental Materials
Abstract
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