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2014
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.Doench, JG, Hartenian E., Graham DB, Tothova Z., Hegde M., Smith I., Sullender M., Ebert BL, Xavier RJ, and Root DE Nature biotechnology, 2014/09/03, (2014) Read More / View Supplemental Materials
Abstract
Genome-scale CRISPR-Cas9 knockout screening in human cells.Shalem, O., Sanjana NE, Hartenian E., Shi X., Scott DA, Mikkelsen TS, Heckl D., Ebert BL, Root DE, Doench JG, and Zhang F. Science (New York, N.Y.), 2014/01/03, Volume 343, Issue 6166, p.84-7, (2014) Read More / View Supplemental Materials
Abstract
2013
Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.Chapuy, B., McKeown MR, Lin CY, Monti S., Roemer MG, Qi J., Rahl PB, Sun HH, Yeda KT, Doench JG, Reichert E., Kung AL, Rodig SJ, Young RA, Shipp M. A., and Bradner JE Cancer cell, 2013/12/09, Volume 24, Issue 6, p.777-90, (2013) Read More / View Supplemental Materials
Abstract
2012
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.Lee, MN, Roy M., Ong SE, Mertins P., Villani AC, Li W., Dotiwala F., Sen J., Doench JG, Orzalli MH, Kramnik I., Knipe DM, Lieberman J., Carr SA, and Hacohen N. Nature immunology, 2012/12/23, Volume 14, Issue 2, p.179-85, (2012) Read More / View Supplemental Materials
Abstract
Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression.Janas, MM, Wang E., Love T., Harris AS, Stevenson K., Semmelmann K., Shaffer JM, Chen PH, Doench JG, Yerramilli SV, Neuberg DS, Iliopoulos D., Housman DE, Burge CB, and Novina CD Molecular cell, 2012/04/27, Volume 46, Issue 2, p.171-86, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-5 of 5 Results