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2014
Immune characterization of P. falciparum parasites with a shared genetic signature in a region of decreasing transmission.Bei, AK, Diouf A., Miura K., Larremore DB, Ribacke U., Tullo G., Moss EL, Neafsey DE, Daniels RF, Zeituni AE, Nosamiefan I., Volkman SK, Ahouidi AD, Ndiaye D., Dieye T., Mboup S., Buckee CO, Long CA, and Wirth DF Infection and immunity, 2014/11/03, (2014) Read More / View Supplemental Materials
Abstract
Clonal outbreak of Plasmodium falciparum in eastern Panama.Obaldia N, 3rd, Baro NK, Calzada JE, Santamaria AM, Daniels R., Wong W., Chang HH, Hamilton EJ, Arevalo-Herrera M., Herrera S., Wirth DF, Hartl DL, Marti M., and Volkman SK The Journal of infectious diseases, 2014/10/21, (2014) Read More / View Supplemental Materials
Abstract
Diversity-Oriented Synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors.Lukens, AK, Heidebrecht RW Jr, Mulrooney C., Beaudoin JA, Comer E., Duvall JR, Fitzgerald ME, Masi D., Galinsky K., Scherer CA, Palmer M., Munoz B., Foley M., Schreiber SL, Wiegand RC, and Wirth DF The Journal of infectious diseases, 2014/10/21, (2014) Read More / View Supplemental Materials
Abstract
Analysis of pfhrp2 genetic diversity in Senegal and implications for use of rapid diagnostic tests.Deme, AB, Park DJ, Bei AK, Sarr O., Badiane AS, Gueye Pel H., Ahouidi A., Ndir O., Mboup S., Wirth DF, Ndiaye D., and Volkman SK Malaria journal, 2014/01/29, Volume 13, Issue 1, p.34, (2014) Read More / View Supplemental Materials
Abstract
Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance.Lukens, AK, Ross LS, Heidebrecht R., Javier Gamo F., Lafuente-Monasterio MJ, Booker ML, Hartl DL, Wiegand RC, and Wirth DF Proceedings of the National Academy of Sciences of the United States of America, 2014/01/14, Volume 111, Issue 2, p.799-804, (2014) Read More / View Supplemental Materials
Abstract
An Adjustable Gas-Mixing Device to Increase Feasibility of In Vitro Culture of Plasmodium falciparum Parasites in the Field.Bei, AK, Patel SD, Volkman SK, Ahouidi AD, Ndiaye D., Mboup S., and Wirth DF PloS one, 2014/01/01, Volume 9, Issue 3, p.e90928, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetic Surveillance Detects Both Clonal and Epidemic Transmission of Malaria following Enhanced Intervention in Senegal.Daniels, R., Chang HH, Séne PD, Park DC, Neafsey DE, Schaffner SF, Hamilton EJ, Lukens AK, Van Tyne D., Mboup S., Sabeti PC, Ndiaye D., Wirth DF, Hartl DL, and Volkman SK PloS one, 2013/01/01, Volume 8, Issue 4, p.e60780, (2013) Read More / View Supplemental Materials
Abstract
2012
Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite.Park, DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C., Ribacke U., Van Tyne D., Galinsky K., Galligan M., Becker JS, Ndiaye D., Mboup S., Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, and Volkman SK Proceedings of the National Academy of Sciences of the United States of America, 2012/08/07, Volume 109, Issue 32, p.13052-7, (2012) Read More / View Supplemental Materials
Abstract
Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population.Chang, HH, Park DJ, Galinsky KJ, Schaffner SF, Ndiaye D., Ndir O., Mboup S., Wiegand RC, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, and Hartl DL Molecular biology and evolution, 2012/06/24, (2012) Read More / View Supplemental Materials
Abstract
Harnessing genomics and genome biology to understand malaria biology.Volkman, SK, Neafsey DE, Schaffner SF, Park DJ, and Wirth DF Nature reviews. Genetics, 2012/04/12, Volume 13, Issue 5, p.315-28, (2012) Read More / View Supplemental Materials
Abstract
Rapid, field-deployable method for genotyping and discovery of drug-resistance single nucleotide polymorphisms in Plasmodium falciparum.Daniels, R., Ndiaye D., Wall M., McKinney J., Séne PD, Sabeti PC, Volkman SK, Mboup S., and Wirth DF Antimicrobial agents and chemotherapy, 2012/03/19, (2012) Read More / View Supplemental Materials
Abstract
Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence.Neafsey, DE, Schaffner SF, Volkman SK, Park D., Montgomery P., Milner DA Jr, Lukens A., Rosen D., Daniels R., Houde N., Cortese JF, Tyndall E., Gates C., Stange-Thomann N., Sarr O., Ndiaye D., Ndir O., Mboup S., Ferreira MU, Moraes Sdo L., et al. Genome biology, 2012/01/07, Volume 9, Issue 12, p.R171, (2012) Read More / View Supplemental Materials
Abstract
2011
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.Urgaonkar, S., Cortese JF, Patel V., Ross L., Clish CB, Serrano AE, Cromwell M., Duraisingh MT, Wirth DF, Clardy J., and Mazitschek R. Chemistry & biology, 2011/12/23, Volume 18, Issue 12, p.1602-10, (2011) Read More / View Supplemental Materials
Abstract
Application of genomics to field investigations of malaria by the international centers of excellence for malaria research.Volkman, SK, Ndiaye D., Diakite M., Koita OA, Nwakanma D., Daniels RF, Park DJ, Neafsey DE, Muskavitch MA, Krogstad DJ, Sabeti PC, Hartl DL, and Wirth DF Acta tropica, 2011/12/13, (2011) Read More / View Supplemental Materials
Abstract
Distribution Pattern of Plasmodium falciparum Chloroquine Transporter (pfcrt) Gene Haplotypes in Sri Lanka 1996-2006.Zhang, JJ, Senaratne TN, Daniels R., Valim C., Alifrangis M., Amerasinghe P., Konradsen F., Rajakaruna R., Wirth DF, and Karunaweera ND The American journal of tropical medicine and hygiene, 2011/11/01, Volume 85, Issue 5, p.811-4, (2011) Read More / View Supplemental Materials
Abstract
Hybrid selection for sequencing pathogen genomes from clinical samples.Melnikov, A., Galinsky K., Rogov P., Fennell T., Van Tyne D., Russ C., Daniels R., Barnes KG, Bochicchio J., Ndiaye D., Sene PD, Wirth DF, Nusbaum C., Volkman SK, Birren BW, Gnirke A., and Neafsey DE Genome biology, 2011/08/11, Volume 12, Issue 8, p.R73, (2011) Read More / View Supplemental Materials
Abstract
Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.Van Tyne, D., Park DJ, Schaffner SF, Neafsey DE, Angelino E., Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA Jr, Johnson CA, Shlyakhter I., Grossman SR, Becker JS, Yamins D., Karlsson EK, Ndiaye D., Sarr O., Mboup S., et al. PLoS genetics, 2011/04/01, Volume 7, Issue 4, p.e1001383, (2011) Read More / View Supplemental Materials
Abstract
2010
SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes.Neafsey, DE, Lawniczak MK, Park DJ, Redmond SN, Coulibaly MB, Traoré SF, Sagnon N., Costantini C., Johnson C., Wiegand RC, Collins FH, Lander E. S., Wirth DF, Kafatos FC, Besansky NJ, Christophides GK, and Muskavitch MA Science (New York, N.Y.), 2010/10/22, Volume 330, Issue 6003, p.514-7, (2010) Read More / View Supplemental Materials
Abstract
A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity.Urgaonkar, S., Cortese JF, Barker RH, Cromwell M., Serrano AE, Wirth DF, Clardy J., and Mazitschek R. Organic letters, 2010/09/17, Volume 12, Issue 18, p.3998-4001, (2010) Read More / View Supplemental Materials
Abstract
2009
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.Patel, V., Mazitschek R., Coleman B., Nguyen C., Urgaonkar S., Cortese J., Barker RH, Greenberg E., Tang W., Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, and Clardy J. Journal of medicinal chemistry, 2009/04/23, Volume 52, Issue 8, p.2185-7, (2009) Read More / View Supplemental Materials
Abstract
2008
A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking.Daniels, R., Volkman SK, Milner DA, Mahesh N., Neafsey DE, Park DJ, Rosen D., Angelino E., Sabeti PC, Wirth DF, and Wiegand RC Malaria journal, 2008/10/29, Volume 7, p.223, (2008) Read More / View Supplemental Materials
Abstract
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.Mazitschek, R., Patel V., Wirth DF, and Clardy J. Bioorganic & medicinal chemistry letters, 2008/05/01, Volume 18, Issue 9, p.2809-12, (2008) Read More / View Supplemental Materials
Abstract
2007
A genome-wide map of diversity in Plasmodium falciparum.Volkman, SK, Sabeti PC, DeCaprio D., Neafsey DE, Schaffner SF, Milner DA Jr, Daily JP, Sarr O., Ndiaye D., Ndir O., Mboup S., Duraisingh MT, Lukens A., Derr A., Stange-Thomann N., Waggoner S., Onofrio R., Ziaugra L., Mauceli E., Gnerre S., et al. Nature genetics, 2007/01/01, Volume 39, Issue 1, p.113-9, (2007) Read More / View Supplemental Materials
Abstract
  • Showing 1-23 of 23 Results