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  • Showing 1-15 of 15 Results
2016
The influence of a short-term gluten-free diet on the human gut microbiome.Bonder, MJ, Tigchelaar EF, Cai X., Trynka G., Cenit MC, Hrdlickova B., Zhong H., Vatanen T., Gevers D., Wijmenga C., Wang Y., and Zhernakova A. Genome medicine, 2016/04/21, Volume 8, Issue 1, p.45, (2016) Read More / View Supplemental Materials
Abstract
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.Gusev, A., Shi H., Kichaev G., Pomerantz M., Li F., Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B., Isaacs WB, Zheng W., Pettaway CA, Yeboah ED, Tettey Y., Biritwum RB, Adjei AA, Tay E., Truelove A., et al. Nature communications, 2016/04/07, Volume 7, p.10979, (2016) Read More / View Supplemental Materials
Abstract
2015
Functional implications of disease-specific variants in loci jointly associated to coeliac disease and rheumatoid arthritis.Gutierrez-Achury, J., Zorro MM, Ricaño-Ponce I., Zhernakova DV, consortium Coeliac Disease Immunochip consortium, RACI, Diogo D., Raychaudhuri S., Franke L., Trynka G., Wijmenga C., and Zhernakova A. Human molecular genetics, 2015/11/05, (2015) Read More / View Supplemental Materials
Abstract
Partitioning heritability by functional annotation using genome-wide association summary statistics.Finucane, HK, Bulik-Sullivan B., Gusev A., Trynka G., Reshef Y., Loh PR, Anttila V., Xu H., Zang C., Farh K., Ripke S., Day FR, ReproGen Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, RACI Consortium, Purcell S., Stahl E., Lindstrom S., Perry JR, Okada Y., et al. Nature genetics, 2015/09/28, (2015) Read More / View Supplemental Materials
Abstract
Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.Trynka, G., Westra HJ, Slowikowski K., Hu X., Xu H., Stranger BE, Klein RJ, Han B., and Raychaudhuri S. American journal of human genetics, 2015/07/02, Volume 97, Issue 1, p.139-52, (2015) Read More / View Supplemental Materials
Abstract
Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.Franke, L., El Bannoudi H., Jansen DT, Kok K., Trynka G., Diogo D., Swertz M., Fransen K., Knevel R., Gutierrez-Achury J., Ärlestig L., Greenberg JD, Kremer J., Pappas DA, Kanterakis A., Weersma RK, van der Helm-van Mil AH, Guryev V., Rantapää-Dahlqvist S., Gregersen PK, et al. European journal of human genetics : EJHG, 2015/05/13, (2015) Read More / View Supplemental Materials
Abstract
Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease.Gutierrez-Achury, J., Zhernakova A., Pulit SL, Trynka G., Hunt KA, Romanos J., Raychaudhuri S., van Heel DA, Wijmenga C., and de Bakker PI Nature genetics, 2015/04/20, (2015) Read More / View Supplemental Materials
Abstract
Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements.Hayes, JE, Trynka G., Vijai J., Offit K., Raychaudhuri S., and Klein RJ PloS one, 2015/01/01, Volume 10, Issue 9, p.e0139360, (2015) Read More / View Supplemental Materials
Abstract
2014
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.Gusev, A., Lee SH, Trynka G., Finucane H., Vilhjálmsson BJ, Xu H., Zang C., Ripke S., Bulik-Sullivan B., Stahl E., Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M., Pasaniuc B., Sullivan PF, Neale BM, et al. American journal of human genetics, 2014/11/06, Volume 95, Issue 5, p.535-52, (2014) Read More / View Supplemental Materials
Abstract
Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells.Hu, X., Im HK, Raj T., Brennan PJ, Trynka G., Teslovich N., Slowikowski K., Chen WM, Onengut S., Baecher-Allan C., De Jager PL, Rich SS, Stranger BE, Brenner MB, and Raychaudhuri S. PLoS genetics, 2014/06/01, Volume 10, Issue 6, p.e1004404, (2014) Read More / View Supplemental Materials
Abstract
Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene.Okada, Y., Diogo D., Greenberg JD, Mouassess F., Achkar WA, Fulton RS, Denny JC, Gupta N., Mirel D., Gabriel S., Li G., Kremer JM, Pappas DA, Carroll RJ, Eyler AE, Trynka G., Stahl EA, Cui J., Saxena R., Coenen MJ, et al. PloS one, 2014/01/01, Volume 9, Issue 2, p.e87645, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases.Trynka, G., and Raychaudhuri S. Current opinion in genetics & development, 2013/12/01, Volume 23, Issue 6, p.635-41, (2013) Read More / View Supplemental Materials
Abstract
Chromatin marks identify critical cell types for fine mapping complex trait variants.Trynka, G., Sandor C., Han B., Xu H., Stranger BE, Liu XS, and Raychaudhuri S. Nature genetics, 2013/02/01, Volume 45, Issue 2, p.124-30, (2013) Read More / View Supplemental Materials
Abstract
2012
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.Stahl, EA, Wegmann D., Trynka G., Gutierrez-Achury J., Do R., Voight BF, Kraft P., Chen R., Kallberg HJ, Kurreeman FA, Diabetes Genetics Replication and Meta-analysis Consortium, Myocardial Infarction Genetics Consortium, Kathiresan S., Wijmenga C., Gregersen PK, Alfredsson L., Siminovitch KA, Worthington J., de Bakker PI, Raychaudhuri S., et al. Nature genetics, 2012/03/25, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-15 of 15 Results