Scientific Publications

Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastasesXu, Lei, Shen Steven S., Hoshida Yujin, Subramanian Aravind, Ross Ken, Brunet Jean-Philippe, Wagner Stephan N., Ramaswamy Sridhar, Mesirov Jill P., and Hynes Richard O. Molecular Cancer Research: MCR, 2008/05//, Volume 6, Issue 5, p.760 - 9, (2008) Read More / View Supplemental Materials

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Abstract

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and diseaseLamb, Justin, Crawford Emily D., Peck David, Modell Joshua W., Blat Irene C., Wrobel Matthew J., Lerner Jim, Brunet Jean-Philippe, Subramanian Aravind, Ross Kenneth N., Reich Michael, Hieronymus Haley, Wei Guo, Armstrong Scott A., Haggarty Stephen J., and Clemons Pau Science (New York, N.Y.), 2006/09/29/, Volume 313, Issue 5795, p.1929 - 35, (2006) Read More / View Supplemental Materials

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Abstract

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profilingBourquin, Jean-Pierre, Subramanian Aravind, Langebrake Claudia, Reinhardt Dirk, Bernard Olivier, Ballerini Paola, and Baruchel Andr Proceedings of the National Academy of Sciences of the United States of America, 2006/02/28/, Volume 103, Issue 9, p.3339 - 44, (2006) Read More / View Supplemental Materials

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Abstract

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformationIsakoff, Michael S., Sansam Courtney G., Tamayo Pablo, Subramanian Aravind, Evans Julia A., Fillmore Christine M., Wang Xi, Biegel Jaclyn A., Pomeroy Scott L., Mesirov Jill P., and Roberts Charles W. M. Proceedings of the National Academy of Sciences of the United States of America, 2005/12/06/, Volume 102, Issue 49, p.17745 - 50, (2005) Read More / View Supplemental Materials

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Abstract

Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasisPegtel, Dirk M., Subramanian Aravind, Sheen Tzung-Shiahn, Tsai Ching-Hwa, Golub Todd R., and Thorley-Lawson David A. Journal of Virology, 2005/12//, Volume 79, Issue 24, p.15430 - 42, (2005) Read More / View Supplemental Materials

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Abstract

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesSubramanian, Aravind, Tamayo Pablo, Mootha Vamsi K., Mukherjee Sayan, Ebert Benjamin L., Gillette Michael A., Paulovich Amanda, Pomeroy Scott L., Golub Todd R., Lander Eric S., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2005/10/25/, Volume 102, Issue 43, p.15545 - 50, (2005) Read More / View Supplemental Materials

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Abstract

A zebrafish bmyb mutation causes genome instability and increased cancer susceptibilityShepard, Jennifer L., Amatruda James F., Stern Howard M., Subramanian Aravind, Finkelstein David, Ziai James, Finley Rose K., Pfaff Kathleen L., Hersey Candace, Zhou Yi, Barut Bruce, Freedman Matthew, Lee Charles, Spitsbergen Jan, Neuberg Donna, and Weber Gerhard Proceedings of the National Academy of Sciences of the United States of America, 2005/09/13/, Volume 102, Issue 37, p.13194 - 9, (2005) Read More / View Supplemental Materials

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Abstract

An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarrayEbert, Benjamin L., Lee Michele M., Pretz Jennifer L., Subramanian Aravind, Mak Raymond, Golub Todd R., and Sieff Colin A. Blood, 2005/06/15/, Volume 105, Issue 12, p.4620 - 6, (2005) Read More / View Supplemental Materials

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Abstract

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysisSweet-Cordero, Alejandro, Mukherjee Sayan, Subramanian Aravind, You Han, Roix Jeffrey J., Ladd-Acosta Christine, Mesirov Jill, Golub Todd R., and Jacks Tyler Nature Genetics, 2005/01//, Volume 37, Issue 1, p.48 - 55, (2005) Read More / View Supplemental Materials

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Abstract

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesMootha, Vamsi K., Lindgren Cecilia M., Eriksson Karl-Fredrik, Subramanian Aravind, Sihag Smita, Lehar Joseph, Puigserver Pere, Carlsson Emma, and Ridderstr Nature Genetics, 2003/07//, Volume 34, Issue 3, p.267 - 73, (2003) Read More / View Supplemental Materials

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Abstract