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2014
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.De Jager, PL, Srivastava G., Lunnon K., Burgess J., Schalkwyk LC, Yu L., Eaton ML, Keenan BT, Ernst J., McCabe C., Tang A., Raj T., Replogle J., Brodeur W., Gabriel S., Chai HS, Younkin C., Younkin SG, Zou F., Szyf M., et al. Nature neuroscience, 2014/09/01, Volume 17, Issue 9, p.1156-1163, (2014) Read More / View Supplemental Materials
Abstract
Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells.Hu, X., Im HK, Raj T., Brennan PJ, Trynka G., Teslovich N., Slowikowski K., Chen WM, Onengut S., Baecher-Allan C., De Jager PL, Rich SS, Stranger BE, Brenner MB, and Raychaudhuri S. PLoS genetics, 2014/06/01, Volume 10, Issue 6, p.e1004404, (2014) Read More / View Supplemental Materials
Abstract
Common genetic variants modulate pathogen-sensing responses in human dendritic cells.Lee, MN, Ye C., Villani AC, Raj T., Li W., Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K., Ward LD, Raddassi K., McCabe C., Lee MH, Frohlich IY, Hafler DA, Kellis M., Raychaudhuri S., Zhang F., Stranger BE, et al. Science (New York, N.Y.), 2014/03/07, Volume 343, Issue 6175, p.1246980, (2014) Read More / View Supplemental Materials
Abstract
Allele-specific methylation occurs at genetic variants associated with complex disease.Hutchinson, JN, Raj T., Fagerness J., Stahl E., Viloria FT, Gimelbrant A., Seddon J., Daly M., Chess A., and Plenge R. PloS one, 2014/01/01, Volume 9, Issue 6, p.e98464, (2014) Read More / View Supplemental Materials
Abstract
Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene.Okada, Y., Diogo D., Greenberg JD, Mouassess F., Achkar WA, Fulton RS, Denny JC, Gupta N., Mirel D., Gabriel S., Li G., Kremer JM, Pappas DA, Carroll RJ, Eyler AE, Trynka G., Stahl EA, Cui J., Saxena R., Coenen MJ, et al. PloS one, 2014/01/01, Volume 9, Issue 2, p.e87645, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects.Patsopoulos, NA, Barcellos LF, Hintzen RQ, Schaefer C., van Duijn CM, Noble JA, Raj T., IMSGC, ANZgene, Gourraud PA, Stranger BE, Oksenberg J., Olsson T., Taylor BV, Sawcer S., Hafler DA, Carrington M., De Jager PL, and de Bakker PI PLoS genetics, 2013/11/01, Volume 9, Issue 11, p.e1003926, (2013) Read More / View Supplemental Materials
Abstract
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.Bradshaw, EM, Chibnik LB, Keenan BT, Ottoboni L., Raj T., Tang A., Rosenkrantz LL, Imboywa S., Lee M., Von Korff A., Alzheimer Disease Neuroimaging Initiative, Morris MC, Evans DA, Johnson K., Sperling RA, Schneider JA, Bennett DA, and De Jager PL Nature neuroscience, 2013/07/01, Volume 16, Issue 7, p.848-50, (2013) Read More / View Supplemental Materials
Abstract
Common risk alleles for inflammatory diseases are targets of recent positive selection.Raj, T., Kuchroo M., Replogle JM, Raychaudhuri S., Stranger BE, and De Jager PL American journal of human genetics, 2013/04/04, Volume 92, Issue 4, p.517-29, (2013) Read More / View Supplemental Materials
Abstract
2012
Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection.Raj, T., Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, and De Jager PL American journal of human genetics, 2012/04/06, Volume 90, Issue 4, p.720-6, (2012) Read More / View Supplemental Materials
Abstract
2011
A genome-wide scan for common variants affecting the rate of age-related cognitive decline.De Jager, PL, Shulman JM, Chibnik LB, Keenan BT, Raj T., Wilson RS, Yu L., Leurgans SE, Tran D., Aubin C., Anderson CD, Biffi A., Corneveaux JJ, Huentelman MJ, Alzheimer's Disease Neuroimaging Initiative, Rosand J., Daly M. J., Myers AJ, Reiman EM, Bennett DA, et al. Neurobiology of aging, 2011/11/03, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-11 of 11 Results