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  • Showing 1-11 of 11 Results
2014
Allelic Expression of Deleterious Protein-Coding Variants across Human Tissues.Kukurba, KR, Zhang R., Li X., Smith KS, Knowles DA, How Tan M., Piskol R., Lek M., Snyder M., Macarthur DG, Li JB, and Montgomery SB PLoS genetics, 2014/05/01, Volume 10, Issue 5, p.e1004304, (2014) Read More / View Supplemental Materials
Abstract
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells.Krönke, J., Udeshi ND, Narla A., Grauman P., Hurst SN, McConkey M., Svinkina T., Heckl D., Comer E., Li X., Ciarlo C., Hartman E., Munshi N., Schenone M., Schreiber SL, Carr SA, and Ebert BL Science (New York, N.Y.), 2014/01/17, Volume 343, Issue 6168, p.301-5, (2014) Read More / View Supplemental Materials
Abstract
2013
Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
Abstract
2012
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis.Rosenbluh, J., Nijhawan D., Cox AG, Li X., Schafer EJ, Zack TI, Wang X., Tsherniak A., Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F., Cowley GS, Root DE, Mesirov J. P., Beroukhim R., and Hahn WC Cell, 2012/12/21, Volume 151, Issue 7, p.1457-73, (2012) Read More / View Supplemental Materials
Abstract
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.Wen, Q., Goldenson B., Silver SJ, Schenone M., Dancik V., Huang Z., Wang LZ, Lewis TA, An WF, Li X., Bray MA, Thiollier C., Diebold L., Gilles L., Vokes MS, Moore CB, Bliss-Moreau M., VerPlank L., Tolliday NJ, Mishra R., et al. Cell, 2012/08/03, Volume 150, Issue 3, p.575-89, (2012) Read More / View Supplemental Materials
Abstract
Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC.Ong, SE, Li X., Schenone M., Schreiber SL, and Carr SA Methods in molecular biology (Clifton, N.J.), 2012/01/09, Volume 803, p.129-40, (2012) Read More / View Supplemental Materials
Abstract
2011
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.Raj, L., Ide T., Gurkar AU, Foley M., Schenone M., Li X., Tolliday NJ, Golub T. R., Carr SA, Shamji AF, Stern AM, Mandinova A., Schreiber SL, and Lee SW Nature, 2011/07/13, Volume 475, Issue 7355, p.231-4, (2011) Read More / View Supplemental Materials
Abstract
2010
International network of cancer genome projects.International Cancer Genome, Consortium, Hudson T. J., Anderson W., Artez A., Barker AD, Bell C., Bernabé RR, Bhan MK, Calvo F., Eerola I., Gerhard DS, Guttmacher A., Guyer M., Hemsley FM, Jennings JL, Kerr D., Klatt P., Kolar P., Kusada J., Lane DP, et al. Nature, 2010/04/15, Volume 464, Issue 7291, p.993-8, (2010) Read More / View Supplemental Materials
Abstract
2009
Identifying the proteins to which small-molecule probes and drugs bind in cells.Ong, SE, Schenone M., Margolin AA, Li X., Do K., Doud MK, Mani D. R., Kuai L., Wang X., Wood JL, Tolliday NJ, Koehler AN, Marcaurelle LA, Golub T. R., Gould RJ, Schreiber SL, and Carr SA Proceedings of the National Academy of Sciences of the United States of America, 2009/03/24, Volume 106, Issue 12, p.4617-22, (2009) Read More / View Supplemental Materials
Abstract
2006
Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics.Tolliday, N., Clemons PA, Ferraiolo P., Koehler AN, Lewis TA, Li X., Schreiber SL, Gerhard DS, and Eliasof S. Cancer research, 2006/09/15, Volume 66, Issue 18, p.8935-42, (2006) Read More / View Supplemental Materials
Abstract
2005
Convergent diversity-oriented synthesis of small-molecule hybrids.Chen, C., Li X., Neumann CS, Lo MM, and Schreiber SL Angewandte Chemie (International ed. in English), 2005/04/08, Volume 44, Issue 15, p.2249-52, (2005) Read More / View Supplemental Materials
  • Showing 1-11 of 11 Results