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  • Showing 1-21 of 21 Results
2012
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.Barretina, J., Caponigro G., Stransky N., Venkatesan K., Margolin AA, Kim S., Wilson CJ, Lehár J., Kryukov GV, Sonkin D., Reddy A., Liu M., Murray L., Berger MF, Monahan JE, Morais P., Meltzer J., Korejwa A., Jané-Valbuena J., Mapa FA, et al. Nature, 2012/03/28, Volume 483, Issue 7391, p.603-7, (2012) Read More / View Supplemental Materials
Abstract
2011
RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors.Oberholzer, PA, Kee D., Dziunycz P., Sucker A., Kamsukom N., Jones R., Roden C., Chalk CJ, Ardlie K., Palescandolo E., Piris A., Macconaill LE, Robert C., Hofbauer GF, McArthur GA, Schadendorf D., and Garraway LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/11/07, (2011) Read More / View Supplemental Materials
Abstract
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.Bass, AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y., Cibulskis K., Sougnez C., Voet D., Saksena G., Sivachenko A., Jing R., Parkin M., Pugh T., Verhaak RG, Stransky N., Boutin AT, Barretina J., Solit DB, Vakiani E., Shao W., et al. Nature genetics, 2011/09/04, Volume 43, Issue 10, p.964-8, (2011) Read More / View Supplemental Materials
Abstract
The mutational landscape of head and neck squamous cell carcinoma.Stransky, N., Egloff AM, Tward AD, Kostic AD, Cibulskis K., Sivachenko A., Kryukov GV, Lawrence MS, Sougnez C., McKenna A., Shefler E., Ramos AH, Stojanov P., Carter SL, Voet D., Cortés ML, Auclair D., Berger MF, Saksena G., Guiducci C., et al. Science (New York, N.Y.), 2011/08/26, Volume 333, Issue 6046, p.1157-60, (2011) Read More / View Supplemental Materials
Abstract
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.Cheung, HW, Cowley GS, Weir BA, Boehm JS, Rusin S., Scott JA, East A., Ali LD, Lizotte PH, Wong TC, Jiang G., Hsiao J., Mermel CH, Getz G., Barretina J., Gopal S., Tamayo P., Gould J., Tsherniak A., Stransky N., et al. Proceedings of the National Academy of Sciences of the United States of America, 2011/07/26, Volume 108, Issue 30, p.12372-7, (2011) Read More / View Supplemental Materials
Abstract
Initial genome sequencing and analysis of multiple myeloma.Chapman, MA, Lawrence MS, Keats JJ, Cibulskis K., Sougnez C., Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M., Anderson KC, Ardlie KG, Auclair D., Baker A., Bergsagel PL, Bernstein BE, Drier Y., Fonseca R., Gabriel SB, Hofmeister CC, et al. Nature, 2011/03/24, Volume 471, Issue 7339, p.467-72, (2011) Read More / View Supplemental Materials
Abstract
The genomic complexity of primary human prostate cancer.Berger, MF, Lawrence MS, Demichelis F., Drier Y., Cibulskis K., Sivachenko AY, Sboner A., Esgueva R., Pflueger D., Sougnez C., Onofrio R., Carter SL, Park K., Habegger L., Ambrogio L., Fennell T., Parkin M., Saksena G., Voet D., Ramos AH, et al. Nature, 2011/02/10, Volume 470, Issue 7333, p.214-20, (2011) Read More / View Supplemental Materials
Abstract
2010
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.Johannessen, CM, Boehm JS, Kim SY, Thomas SR, Wardwell L., Johnson LA, Emery CM, Stransky N., Cogdill AP, Barretina J., Caponigro G., Hieronymus H., Murray RR, Salehi-Ashtiani K., Hill DE, Vidal M., Zhao JJ, Yang X., Alkan O., Kim S., et al. Nature, 2010/12/16, Volume 468, Issue 7326, p.968-72, (2010) Read More / View Supplemental Materials
Abstract
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.Barretina, J., Taylor BS, Banerji S., Ramos AH, Lagos-Quintana M., Decarolis PL, Shah K., Socci ND, Weir BA, Ho A., Chiang DY, Reva B., Mermel CH, Getz G., Antipin Y., Beroukhim R., Major JE, Hatton C., Nicoletti R., Hanna M., et al. Nature genetics, 2010/08/01, Volume 42, Issue 8, p.715-21, (2010) Read More / View Supplemental Materials
Abstract
Integrative analysis of the melanoma transcriptome.Berger, MF, Levin JZ, Vijayendran K., Sivachenko A., Adiconis X., Maguire J., Johnson LA, Robinson J., Verhaak RG, Sougnez C., Onofrio RC, Ziaugra L., Cibulskis K., Laine E., Barretina J., Winckler W., Fisher DE, Getz G., Meyerson M., Jaffe DB, et al. Genome research, 2010/04/01, Volume 20, Issue 4, p.413-27, (2010) Read More / View Supplemental Materials
Abstract
The landscape of somatic copy-number alteration across human cancers.Beroukhim, R., Mermel CH, Porter D., Wei G., Raychaudhuri S., Donovan J., Barretina J., Boehm JS, Dobson J., Urashima M., Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L., Greulich H., Reich M., Winckler W., Lawrence MS, Weir BA, et al. Nature, 2010/02/18, Volume 463, Issue 7283, p.899-905, (2010) Read More / View Supplemental Materials
Abstract
2009
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.Vasudevan, KM, Barbie DA, Davies MA, Rabinovsky R., McNear CJ, Kim JJ, Hennessy BT, Tseng H., Pochanard P., Kim SY, Dunn IF, Schinzel AC, Sandy P., Hoersch S., Sheng Q., Gupta PB, Boehm JS, Reiling JH, Silver S., Lu Y., et al. Cancer cell, 2009/07/07, Volume 16, Issue 1, p.21-32, (2009) Read More / View Supplemental Materials
Abstract
Applications of genomics in melanoma oncogene discovery.Berger, MF, and Garraway LA Hematology/oncology clinics of North America, 2009/06/01, Volume 23, Issue 3, p.397-414, vii, (2009) Read More / View Supplemental Materials
Abstract
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation.Salvesen, HB, Carter SL, Mannelqvist M., Dutt A., Getz G., Stefansson IM, Raeder MB, Sos ML, Engelsen IB, Trovik J., Wik E., Greulich H., Bø TH, Jonassen I., Thomas RK, Zander T., Garraway LA, Oyan AM, Sellers WR, Kalland KH, et al. Proceedings of the National Academy of Sciences of the United States of America, 2009/03/24, Volume 106, Issue 12, p.4834-9, (2009) Read More / View Supplemental Materials
Abstract
2008
Modeling genomic diversity and tumor dependency in malignant melanoma.Lin, WM, Baker AC, Beroukhim R., Winckler W., Feng W., Marmion JM, Laine E., Greulich H., Tseng H., Gates C., Hodi FS, Dranoff G., Sellers WR, Thomas RK, Meyerson M., Golub T. R., Dummer R., Herlyn M., Getz G., and Garraway LA Cancer research, 2008/02/01, Volume 68, Issue 3, p.664-73, (2008) Read More / View Supplemental Materials
Abstract
2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.Beroukhim, R., Getz G., Nghiemphu L., Barretina J., Hsueh T., Linhart D., Vivanco I., Lee JC, Huang JH, Alexander S., Du J., Kau T., Thomas RK, Shah K., Soto H., Perner S., Prensner J., Debiasi RM, Demichelis F., Hatton C., et al. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.20007-12, (2007) Read More / View Supplemental Materials
Abstract
Characterizing the cancer genome in lung adenocarcinoma.Weir, BA, Woo MS, Getz G., Perner S., Ding L., Beroukhim R., Lin WM, Province MA, Kraja A., Johnson LA, Shah K., Sato M., Thomas RK, Barletta JA, Borecki IB, Broderick S., Chang AC, Chiang DY, Chirieac LR, Cho J., et al. Nature, 2007/12/06, Volume 450, Issue 7171, p.893-8, (2007) Read More / View Supplemental Materials
Abstract
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.Boehm, JS, Zhao JJ, Yao J., Kim SY, Firestein R., Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S., Richardson AL, Greulich H., Stewart CJ, Mulvey LA, Shen RR, Ambrogio L., Hirozane-Kishikawa T., Hill DE, Vidal M., Meyerson M., Grenier JK, et al. Cell, 2007/06/15, Volume 129, Issue 6, p.1065-79, (2007) Read More / View Supplemental Materials
Abstract
High-throughput oncogene mutation profiling in human cancer.Thomas, RK, Baker AC, Debiasi RM, Winckler W., LaFramboise T., Lin WM, Wang M., Feng W., Zander T., MacConaill L., Lee JC, Nicoletti R., Hatton C., Goyette M., Girard L., Majmudar K., Ziaugra L., Wong KK, Gabriel S., Beroukhim R., et al. Nature genetics, 2007/03/01, Volume 39, Issue 3, p.347-51, (2007) Read More / View Supplemental Materials
Abstract
2006
BRAF mutation predicts sensitivity to MEK inhibition.Solit, DB, Garraway LA, Pratilas CA, Sawai A., Getz G., Basso A., Ye Q., Lobo JM, She Y., Osman I., Golub T. R., Sebolt-Leopold J., Sellers WR, and Rosen N. Nature, 2006/01/19, Volume 439, Issue 7074, p.358-62, (2006) Read More / View Supplemental Materials
Abstract
2005
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.Garraway, LA, Widlund HR, Rubin MA, Getz G., Berger AJ, Ramaswamy S., Beroukhim R., Milner DA, Granter SR, Du J., Lee C., Wagner SN, Li C., Golub T. R., Rimm DL, Meyerson ML, Fisher DE, and Sellers WR Nature, 2005/07/07, Volume 436, Issue 7047, p.117-22, (2005) Read More / View Supplemental Materials
Abstract
  • Showing 1-21 of 21 Results