Scientific Publications

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.Brastianos, PK, Horowitz PM, Santagata S., Jones RT, McKenna A., Getz G., Ligon KL, Palescandolo E., Van Hummelen P., Ducar MD, Raza A., Sunkavalli A., Macconaill LE, Stemmer-Rachamimov AO, Louis DN, Hahn WC, Dunn IF, and Beroukhim R. Nature genetics, 2013/01/20, (2013) Read More / View Supplemental Materials

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Abstract

High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing.Wagle, N., Berger MF, Davis MJ, Blumenstiel B., DeFelice M., Pochanard P., Ducar M., Van Hummelen P., Macconaill LE, Hahn WC, Meyerson M., Gabriel SB, and Garraway LA Cancer discovery, 2012/01/01, Volume 2, Issue 1, p.82-93, (2012) Read More / View Supplemental Materials

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Abstract

RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors.Oberholzer, PA, Kee D., Dziunycz P., Sucker A., Kamsukom N., Jones R., Roden C., Chalk CJ, Ardlie K., Palescandolo E., Piris A., Macconaill LE, Robert C., Hofbauer GF, McArthur GA, Schadendorf D., and Garraway LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/11/07, (2011) Read More / View Supplemental Materials

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Abstract

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling.Wagle, N., Emery C., Berger MF, Davis MJ, Sawyer A., Pochanard P., Kehoe SM, Johannessen CM, Macconaill LE, Hahn WC, Meyerson M., and Garraway LA Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011/08/01, Volume 29, Issue 22, p.3085-96, (2011) Read More / View Supplemental Materials

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Abstract