Recent Broad Publications

Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.
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Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.
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Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.
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miR-155 in Acute Myeloid Leukemia: Not Merely a Prognostic Marker?
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Scientific Publications

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Filters: Author is Jänne, PA [Clear All Filters]

2012

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.Imielinski, M., Berger AH, Hammerman PS, Hernandez B., Pugh TJ, Hodis E., Cho J., Suh J., Capelletti M., Sivachenko A., Sougnez C., Auclair D., Lawrence MS, Stojanov P., Cibulskis K., Choi K., de Waal L., Sharifnia T., Brooks A., Greulich H., et al. Cell, 2012/09/14, Volume 150, Issue 6, p.1107-20, (2012) Read More / View Supplemental Materials

Circumventing cancer drug resistance in the era of personalized medicine.Garraway, LA, and Jänne PA Cancer discovery, 2012/03/01, Volume 2, Issue 3, p.214-26, (2012) Read More / View Supplemental Materials

2011

Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers.Cheung, HW, Du J., Boehm JS, He F., Weir BA, Wang X., Butaney M., Sequist LV, Luo B., Engelman JA, Root DE, Meyerson M., Golub T. R., Jänne PA, and Hahn WC Cancer discovery, 2011/12/01, Volume 1, Issue 7, p.608-25, (2011) Read More / View Supplemental Materials

2005

Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants.Greulich, H., Chen TH, Feng W., Jänne PA, Alvarez JV, Zappaterra M., Bulmer SE, Frank DA, Hahn WC, Sellers WR, and Meyerson M. PLoS medicine, 2005/11/01, Volume 2, Issue 11, p.e313, (2005) Read More / View Supplemental Materials

2004

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.Paez, JG, Jänne PA, Lee JC, Tracy S., Greulich H., Gabriel S., Herman P., Kaye FJ, Lindeman N., Boggon TJ, Naoki K., Sasaki H., Fujii Y., Eck MJ, Sellers WR, Johnson B. E., and Meyerson M. Science (New York, N.Y.), 2004/06/04, Volume 304, Issue 5676, p.1497-500, (2004) Read More / View Supplemental Materials

High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines.Jänne, PA, Li C., Zhao X., Girard L., Chen TH, Minna J., Christiani DC, Johnson B. E., and Meyerson M. Oncogene, 2004/04/08, Volume 23, Issue 15, p.2716-26, (2004) Read More / View Supplemental Materials