Recent Broad Publications

Small-Molecule Inhibitors of Cytokine-Mediated STAT1 Signal Transduction in β-Cells with Improved Aqueous Solubility.
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Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.
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Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.
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Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.
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miR-155 in Acute Myeloid Leukemia: Not Merely a Prognostic Marker?
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Scientific Publications

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2012

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.Birsoy, K., Wang T., Possemato R., Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y., Peterson TR, Carette JE, Brummelkamp TR, Clish CB, and Sabatini DM Nature genetics, 2012/12/16, Volume 45, Issue 1, p.104-8, (2012) Read More / View Supplemental Materials

2010

Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.Boulbes, D., Chen CH, Shaikenov T., Agarwal NK, Peterson TR, Addona TA, Keshishian H., Carr SA, Magnuson MA, Sabatini DM, and Sarbassov dos D. Molecular cancer research : MCR, 2010/06/01, Volume 8, Issue 6, p.896-906, (2010) Read More / View Supplemental Materials

2007

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.Sancak, Y., Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E., Carr SA, and Sabatini DM Molecular cell, 2007/03/23, Volume 25, Issue 6, p.903-15, (2007) Read More / View Supplemental Materials