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  • Showing 1-22 of 22 Results
2016
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.Tirosh, I., Izar B., Prakadan SM, Wadsworth MH 2nd, Treacy D., Trombetta JJ, Rotem A., Rodman C., Lian C., Murphy G., Fallahi-Sichani M., Dutton-Regester K., Lin JR, Cohen O., Shah P., Lu D., Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, et al. Science (New York, N.Y.), 2016/04/08, Volume 352, Issue 6282, p.189-96, (2016) Read More / View Supplemental Materials
Abstract
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.Wong, AS, Choi GC, Cui CH, Pregernig G., Milani P., Adam M., Perli SD, Kazer SW, Gaillard A., Hermann M., Shalek AK, Fraenkel E., and Lu TK Proceedings of the National Academy of Sciences of the United States of America, 2016/02/10, (2016) Read More / View Supplemental Materials
Abstract
Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.Kløverpris, HN, Kazer SW, Mjösberg J., Mabuka JM, Wellmann A., Ndhlovu Z., Yadon MC, Nhamoyebonde S., Muenchhoff M., Simoni Y., Andersson F., Kuhn W., Garrett N., Burgers WA, Kamya P., Pretorius K., Dong K., Moodley A., Newell EW, Kasprowicz V., et al. Immunity, 2016/02/01, (2016) Read More / View Supplemental Materials
Abstract
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.Kimmerling, RJ, Lee Szeto G., Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J., Blainey PC, Irvine DJ, Shalek AK, and Manalis SR Nature communications, 2016/01/06, Volume 7, p.10220, (2016) Read More / View Supplemental Materials
Abstract
2015
Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity.Gaublomme, JT, Yosef N., Lee Y., Gertner RS, Yang LV, Wu C., Pandolfi PP, Mak T., Satija R., Shalek AK, Kuchroo VK, Park H., and Regev A. Cell, 2015/11/18, (2015) Read More / View Supplemental Materials
Abstract
Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses.Avraham, R., Haseley N., Brown D., Penaranda C., Jijon HB, Trombetta JJ, Satija R., Shalek AK, Xavier RJ, Regev A., and Hung DT Cell, 2015/09/10, Volume 162, Issue 6, p.1309-21, (2015) Read More / View Supplemental Materials
Abstract
Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics.Wadsworth MH, 2nd, Hughes TK, and Shalek AK Genome biology, 2015/06/20, Volume 16, Issue 1, p.129, (2015) Read More / View Supplemental Materials
Abstract
MERFISHing for spatial context.Shalek, AK, and Satija R. Trends in immunology, 2015/05/23, (2015) Read More / View Supplemental Materials
Abstract
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets.Macosko, EZ, Basu A., Satija R., Nemesh J., Shekhar K., Goldman M., Tirosh I., Bialas AR, Kamitaki N., Martersteck EM, Trombetta JJ, Weitz DA, Sanes JR, Shalek AK, Regev A., and McCarroll SA Cell, 2015/05/21, Volume 161, Issue 5, p.1202-14, (2015) Read More / View Supplemental Materials
Abstract
2014
Deconstructing transcriptional heterogeneity in pluripotent stem cells.Kumar, RM, Cahan P., Shalek AK, Satija R., DaleyKeyser AJ, Li H., Zhang J., Pardee K., Gennert D., Trombetta JJ, Ferrante TC, Regev A., Daley GQ, and Collins JJ Nature, 2014/12/04, Volume 516, Issue 7529, p.56-61, (2014) Read More / View Supplemental Materials
Abstract
Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing.Trombetta, JJ, Gennert D., Lu D., Satija R., Shalek AK, and Regev A. Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.], 2014/07/01, Volume 107, p.4.22.1-4.22.17, (2014) Read More / View Supplemental Materials
Abstract
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.Patel, AP, Tirosh I., Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H., Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O., Suvà ML, Regev A., and Bernstein BE Science (New York, N.Y.), 2014/06/20, Volume 344, Issue 6190, p.1396-401, (2014) Read More / View Supplemental Materials
Abstract
Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.Shalek, AK, Satija R., Shuga J., Trombetta JJ, Gennert D., Lu D., Chen P., Gertner RS, Gaublomme JT, Yosef N., Schwartz S., Fowler B., Weaver S., Wang J., Wang X., Ding R., Raychowdhury R., Friedman N., Hacohen N., Park H., et al. Nature, 2014/06/19, Volume 509, Issue 7505, p.363-9, (2014) Read More / View Supplemental Materials
Abstract
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.Lohr, JG, Adalsteinsson VA, Cibulskis K., Choudhury AD, Rosenberg M., Cruz-Gordillo P., Francis JM, Zhang CZ, Shalek AK, Satija R., Trombetta JJ, Lu D., Tallapragada N., Tahirova N., Kim S., Blumenstiel B., Sougnez C., Lowe A., Wong B., Auclair D., et al. Nature biotechnology, 2014/05/01, Volume 32, Issue 5, p.479-84, (2014) Read More / View Supplemental Materials
Abstract
Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.Wang, L., Shalek AK, Lawrence M., Ding R., Gaublomme JT, Pochet N., Stojanov P., Sougnez C., Shukla SA, Stevenson KE, Zhang W., Wong J., Sievers QL, Macdonald BT, Vartanov AR, Goldstein NR, Neuberg D., He X., Lander E., Hacohen N., et al. Blood, 2014/04/28, (2014) Read More / View Supplemental Materials
Abstract
Heterogeneity in immune responses: from populations to single cells.Satija, R., and Shalek AK Trends in immunology, 2014/04/16, (2014) Read More / View Supplemental Materials
Abstract
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells.Suvà, ML, Rheinbay E., Gillespie SM, Patel AP, Wakimoto H., Rabkin SD, Riggi N., Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N., Kasif S., Beik S., Kadri S., Tirosh I., Wortman I., Shalek AK, et al. Cell, 2014/04/09, (2014) Read More / View Supplemental Materials
Abstract
2013
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells.Shalek, AK, Satija R., Adiconis X., Gertner RS, Gaublomme JT, Raychowdhury R., Schwartz S., Yosef N., Malboeuf C., Lu D., Trombetta JJ, Gennert D., Gnirke A., Goren A., Hacohen N., Levin JZ, Park H., and Regev A. Nature, 2013/06/13, Volume 498, Issue 7453, p.236-40, (2013) Read More / View Supplemental Materials
Abstract
Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.Gifford, CA, Ziller MJ, Gu H., Trapnell C., Donaghey J., Tsankov A., Shalek AK, Kelley DR, Shishkin AA, Issner R., Zhang X., Coyne M., Fostel JL, Holmes L., Meldrim J., Guttman M., Epstein C., Park H., Kohlbacher O., Rinn J., et al. Cell, 2013/05/23, Volume 153, Issue 5, p.1149-63, (2013) Read More / View Supplemental Materials
Abstract
Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli.Gat-Viks, I., Chevrier N., Wilentzik R., Eisenhaure T., Raychowdhury R., Steuerman Y., Shalek AK, Hacohen N., Amit I., and Regev A. Nature biotechnology, 2013/04/01, Volume 31, Issue 4, p.342-9, (2013) Read More / View Supplemental Materials
Abstract
Dynamic regulatory network controlling TH17 cell differentiation.Yosef, N., Shalek AK, Gaublomme JT, Jin H., Lee Y., Awasthi A., Wu C., Karwacz K., Xiao S., Jorgolli M., Gennert D., Satija R., Shakya A., Lu DY, Trombetta JJ, Pillai MR, Ratcliffe PJ, Coleman ML, Bix M., Tantin D., et al. Nature, 2013/03/06, (2013) Read More / View Supplemental Materials
Abstract
2011
Systematic discovery of TLR signaling components delineates viral-sensing circuits.Chevrier, N., Mertins P., Artyomov MN, Shalek AK, Iannacone M., Ciaccio MF, Gat-Viks I., Tonti E., Degrace MM, Clauser KR, Garber M., Eisenhaure TM, Yosef N., Robinson J., Sutton A., Andersen MS, Root DE, von Andrian U., Jones RB, Park H., et al. Cell, 2011/11/11, Volume 147, Issue 4, p.853-67, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-22 of 22 Results