Scientific Publications

Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Fass, DM, Reis SA, Ghosh B., Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W., Barker DD, Mazitschek R., Schreiber SL, Tsai LH, and Haggarty SJ Neuropharmacology, 2012/07/04, (2012) Read More / View Supplemental Materials

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Abstract

An epigenetic blockade of cognitive functions in the neurodegenerating brain.Gräff, J., Rei D., Guan JS, Wang WY, Seo J., Hennig KM, Nieland TJ, Fass DM, Kao PF, Kahn M., Su SC, Samiei A., Joseph N., Haggarty SJ, Delalle I., and Tsai LH Nature, 2012/02/29, (2012) Read More / View Supplemental Materials

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Abstract

Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity.Yu, M., Romer KA, Nieland TJ, Xu S., Saenz-Vash V., Penman M., Yesilaltay A., Carr SA, and Krieger M. Proceedings of the National Academy of Sciences of the United States of America, 2011/07/26, Volume 108, Issue 30, p.12243-8, (2011) Read More / View Supplemental Materials

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Abstract

Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.Nieland, TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S., Zannis VI, Kirchhausen T., and Krieger M. Biochemistry, 2008/01/08, Volume 47, Issue 1, p.460-72, (2008) Read More / View Supplemental Materials

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Abstract

Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.Nieland, TJ, Shaw JT, Jaipuri FA, Maliga Z., Duffner JL, Koehler AN, and Krieger M. Journal of lipid research, 2007/08/01, Volume 48, Issue 8, p.1832-45, (2007) Read More / View Supplemental Materials

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Abstract