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2015
The schizophrenia risk gene product miR-137 alters presynaptic plasticity.Siegert, S., Seo J., Kwon EJ, Rudenko A., Cho S., Wang W., Flood Z., Martorell AJ, Ericsson M., Mungenast AE, and Tsai LH Nature neuroscience, 2015/05/25, (2015) Read More / View Supplemental Materials
Abstract
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.Murn, J., Zarnack K., Yang YJ, Durak O., Murphy EA, Cheloufi S., Gonzalez DM, Teplova M., Curk T., Zuber J., Patel DJ, Ule J., Luscombe NM, Tsai LH, Walsh CA, and Shi Y. Genes & development, 2015/03/01, Volume 29, Issue 5, p.501-12, (2015) Read More / View Supplemental Materials
Abstract
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease.Gjoneska, E., Pfenning AR, Mathys H., Quon G., Kundaje A., Tsai LH, and Kellis M. Nature, 2015/02/19, Volume 518, Issue 7539, p.365-9, (2015) Read More / View Supplemental Materials
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Integrative analysis of 111 reference human epigenomes.Roadmap Epigenomics, Consortium, Kundaje A., Meuleman W., Ernst J., Bilenky M., Yen A., Heravi-Moussavi A., Kheradpour P., Zhang Z., Wang J., Ziller MJ, Amin V., Whitaker JW, Schultz MD, Ward LD, Sarkar A., Quon G., Sandstrom RS, Eaton ML, Wu YC, et al. Nature, 2015/02/19, Volume 518, Issue 7539, p.317-30, (2015) Read More / View Supplemental Materials
Abstract
Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment.Rudenko, A., Seo J., Hu J., Su SC, de Anda FC, Durak O., Ericsson M., Carlén M., and Tsai LH The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015/02/11, Volume 35, Issue 6, p.2372-83, (2015) Read More / View Supplemental Materials
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Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons.Yoshimizu, T., Pan JQ, Mungenast AE, Madison JM, Su S., Ketterman J., Ongur D., McPhie D., Cohen B., Perlis R., and Tsai LH Molecular psychiatry, 2015/02/01, Volume 20, Issue 2, p.162-9, (2015) Read More / View Supplemental Materials
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Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers.Wagner, FF, Zhang YL, Fass DM, Joseph N., Gale JP, Weïwer M., McCarren P., Fisher SL, Kaya T., Zhao WN, Reis SA, Hennig KM, Thomas M., Lemercier BC, Lewis MC, Guan JS, Moyer MP, Scolnick E., Haggarty SJ, Tsai LH, et al. Chemical science (Royal Society of Chemistry : 2010), 2015/01/01, Volume 6, Issue 1, p.804-815, (2015) Read More / View Supplemental Materials
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2014
Early remodeling of the neocortex upon episodic memory encoding.Bero, AW, Meng J., Cho S., Shen AH, Canter RG, Ericsson M., and Tsai LH Proceedings of the National Academy of Sciences of the United States of America, 2014/07/28, (2014) Read More / View Supplemental Materials
Abstract
Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.Durak, O., de Anda FC, Singh KK, Leussis MP, Petryshen TL, Sklar P., and Tsai LH Molecular psychiatry, 2014/05/13, (2014) Read More / View Supplemental Materials
Abstract
Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment.Seo, J., Giusti-Rodríguez P., Zhou Y., Rudenko A., Cho S., Ota KT, Park C., Patzke H., Madabhushi R., Pan L., Mungenast AE, Guan JS, Delalle I., and Tsai LH Cell, 2014/04/10, Volume 157, Issue 2, p.486-98, (2014) Read More / View Supplemental Materials
Abstract
Epigenetic Priming of Memory Updating during Reconsolidation to Attenuate Remote Fear Memories.Gräff, J., Joseph NF, Horn ME, Samiei A., Meng J., Seo J., Rei D., Bero AW, Phan TX, Wagner F., Holson E., Xu J., Sun J., Neve RL, Mach RH, Haggarty SJ, and Tsai LH Cell, 2014/01/16, Volume 156, Issue 1-2, p.261-76, (2014) Read More / View Supplemental Materials
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2013
A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration.Gräff, J., Kahn M., Samiei A., Gao J., Ota KT, Rei D., and Tsai LH The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013/05/22, Volume 33, Issue 21, p.8951-60, (2013) Read More / View Supplemental Materials
Abstract
DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.Soda, T., Frank C., Ishizuka K., Baccarella A., Park YU, Flood Z., Park SK, Sawa A., and Tsai LH Molecular psychiatry, 2013/04/16, (2013) Read More / View Supplemental Materials
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Histone acetylation: molecular mnemonics on the chromatin.Gräff, J., and Tsai LH Nature reviews. Neuroscience, 2013/02/01, Volume 14, Issue 2, p.97-111, (2013) Read More / View Supplemental Materials
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2012
Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Fass, DM, Reis SA, Ghosh B., Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W., Barker DD, Mazitschek R., Schreiber SL, Tsai LH, and Haggarty SJ Neuropharmacology, 2012/07/04, (2012) Read More / View Supplemental Materials
Abstract
An epigenetic blockade of cognitive functions in the neurodegenerating brain.Gräff, J., Rei D., Guan JS, Wang WY, Seo J., Hennig KM, Nieland TJ, Fass DM, Kao PF, Kahn M., Su SC, Samiei A., Joseph N., Haggarty SJ, Delalle I., and Tsai LH Nature, 2012/02/29, (2012) Read More / View Supplemental Materials
Abstract
2011
Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development.Singh, KK, De Rienzo G., Drane L., Mao Y., Flood Z., Madison J., Ferreira M., Bergen S., King C., Sklar P., Sive H., and Tsai LH Neuron, 2011/11/17, Volume 72, Issue 4, p.545-58, (2011) Read More / View Supplemental Materials
Abstract
Synaptic Deficits Are Rescued in the p25/Cdk5 Model of Neurodegeneration by the Reduction of β-Secretase (BACE1).Giusti-Rodríguez, P., Gao J., Gräff J., Rei D., Soda T., and Tsai LH The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011/11/02, Volume 31, Issue 44, p.15751-6, (2011) Read More / View Supplemental Materials
Abstract
2009
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.Mao, Y., Ge X., Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C., Berry EM, Soda T., Singh KK, Biechele T., Petryshen TL, Moon RT, Haggarty SJ, and Tsai LH Cell, 2009/03/20, Volume 136, Issue 6, p.1017-31, (2009) Read More / View Supplemental Materials
Abstract
  • Showing 1-19 of 19 Results